Results 141 to 150 of about 44,076 (327)

ВОСПРОИЗВОДИТЕЛЬНЫЕ КАЧЕСТВА СВИНОМАТОК ПРИ ПОМЕСНОМ СКРЕЩИВАНИИ

open access: yesВетеринарная патология, 2010
Authors study reproductive qualities of sows at various variants of two-pedigree industrial crossing. Sows of large black breed covered with male pigs durok have appeared the most productive.

doaj  

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

A tool to optimise dairy herd replacements combining conventional, sexed, and beef semen

open access: yesItalian Journal of Animal Science
A tool to help Italian dairy farmers choosing the most suitable replacement strategy has been developed. The approach aimed to identify yearly female replacement needs based on herd performance level and combination of different semen type (conventional,
Valentina Ferrari   +5 more
doaj   +1 more source

Rotational crossbreeding systems for pork producers (1993) [PDF]

open access: yes, 1993
More than 90 percent of hogs marketed are of mixed breeding, an indication that crossbreeding is a well accepted management program. Yet crossbreeding alone does not guarantee efficient, profitable production. Choosing the system and breeds that fit your
Bates, Ronald Oscar, 1959-
core  

Association of CDKN2A/B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai   +13 more
wiley   +1 more source

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen   +10 more
wiley   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick   +19 more
wiley   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

Comparative growth, production, carcass characteristics and reproduction performance of Naked Neck, Black Australorp and their crossbred chicken

open access: yesItalian Journal of Animal Science
This study evaluated the phenotypic and genetic parameters of indigenous Naked Neck (NN), exotic Black Australorp (BA), and their crossbred (NNBA) chickens. A total of 270 day-old chicks (30 per group) were raised under identical conditions from day 1 to
Mohammad Alam   +7 more
doaj   +1 more source

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