Results 151 to 160 of about 45,029 (376)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Effects of Crossbreeding and Concentrates Feeding on Growth Rates of Goat Kids Reared under Highlands Conditions

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Aim of the current research was to evaluate the effects that crossbreeding and concentrates feeding have on growth performance of goat kids managed under pasture conditions of the Romanian highlands.
Maria Sauer   +5 more
doaj  

Participatory breeding system for laying hens [PDF]

open access: yes, 2010
Livestock breeds (and breeding systems) developed for intensive production systems often do not perform as expected in organic and extensive systems.
Leenstra, Ferry
core  

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

Comparative Study Regarding Body Development in Turcana and F1 German Blackheaded x Turcana Yearling Ewes

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Researches were carried out in a commercial sheep farm from Arad County, situated in western Romania. Yearling ewes, with their age ranging from 12 to 13 months were included in the trial. Two genotypes were considered, purebred indigenous Turcana (TA, n
Ioan Pădeanu   +6 more
doaj  

Crossbreeding in Swine: Experimental Results

open access: yesJournal of Animal Science, 1981
Summary A review of recent swine crossbreeding experiments is presented and integrated with earlier work. Variation among experiments in observed heterosis for specific crosses was large for reproduction and sow productivity traits. However, standard errors of estimates were also large. It seems likely that heterosis, expressed in absolute values or in
openaire   +3 more sources

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

open access: yesMolecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo   +6 more
wiley   +1 more source

Performance of beef cows of different genetic groups in natural and cultivated pastures

open access: yesBioscience Journal, 2016
The objective was to assess the performance of 96 pregnant cows of the genetic groups (GG) Charolais (C), Nellore (N), ½ CN and ½ NC, subjected to the following treatments: kept exclusively in natural pastures (NP) throughout the experimental period ...
Ricardo Zambarda Vaz   +7 more
doaj  

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

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