Results 101 to 110 of about 309,911 (313)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The comparative study of several big wooden crosses painted by Giotto allowed to deepen the work organization in the Middle Ages’ workshop. This analysis found several analogies of execution between the works, by demonstrating that the production of ...
Daphné de Luca
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
The paper reports the theory and practice of using sex-linked crosses and autosexing breeds in poultry breeding and production.
Bondarenko, Yu V, Romanov, Michael N
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
DIALLEL CROSSES FOR IMPROVING FABA BEAN (Vicia faba L.) UNDER RAIN-FED CONDITIONS: 1. YIELD AND YIELD COMPONENTS [PDF]
A. El-Hosary +4 more
doaj +1 more source
''Marian Murphy, Nancy Hunter, Janet Collins (L-R), making palm crosses. Crosses, made by the Girl's Service Guild will be distributed to members of the congregation attending Sunday services at St. Mark's Episcopal Church.'
core
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
The symbols x and + (two forms of crosses) are omnipresent in this work; the work indeed is composed by an orderly permutation for these two symbols.
DING 丁乙, Yi
core

