Results 201 to 210 of about 1,900,755 (354)

Executive Agreements Database, Statement Concerning the Acquisition and Cross-Servicing Agreement with New Zealand, with Annexes Signed At Sydney November 6, 2012 Entered into force November 6, 2012

, 2020
Oona A. Hathaway, Curtis A. Bradley, Jack L. Goldsmith   +2 more
openalex   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Dual genetic mechanisms of heterosis: population structure and gene action. [PDF]

Front Plant Sci
Aguilar FS, Lamkey KR, Edwards JW.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Drosophila wing is a high-throughput and versatile screening tool for Tau-mediated disease mechanisms and drug discovery. [PDF]

Dis Model Mech
Ramirez-Moreno M, Cooper AS, Lian T, Liu J, Abtahi S, Skoulakis EMC, Sivanantharajah L, Allan DW, Mudher A.   +8 more
europepmc   +1 more source

Drosera neesii: Cross, A.

, 2016
IUCN
openalex   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Automated cone photoreceptor detection using synthetic data and deep learning in confocal adaptive optics scanning laser ophthalmoscope images. [PDF]

Sci Rep
Shah M, Young LK, Downes SM, Smithson HE, Namburete AIL.   +4 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Assessment of segregation variance estimates from derivation, simulations, and empirical data in autotetraploid species exemplified in potato. [PDF]

Genetics
Wu PY, Thelen K, Hartje S, Muders K, Prigge V, Stich B, Van Inghelandt D.   +6 more
europepmc   +1 more source