Results 61 to 70 of about 347,640 (269)

Odd Crossing Number and Crossing Number Are Not the Same [PDF]

open access: yesDiscrete & Computational Geometry, 2006
The crossing number \(\text{cr}(G)\) of a graph \(G\) is the minimum number of edge crossings, taken over all drawing of \(G\) in the plane. Similarly \(\text{per}(G)\) (respectively \(\text{ocr}(G)\)) denotes the minimum number of pairs of edges which cross at least once (respectively an odd number of times), over all drawings of \(G\) in the plane ...
Michael J. Pelsmajer   +2 more
openaire   +4 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Computational Experiments with Cross and Crooked Cross Cuts [PDF]

open access: yesINFORMS Journal on Computing, 2014
In this paper, we study whether cuts obtained from two simplex tableau rows at a time can strengthen the bounds obtained by Gomory mixed-integer (GMI) cuts based on single tableau rows. We also study whether cross and crooked cross cuts, which generalize split cuts, can be separated in an effective manner for practical mixed-integer programs (MIPs ...
Sanjeeb Dash   +2 more
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Equity trading by institutional investors: To cross or not to cross? [PDF]

open access: yesJournal of Financial Markets, 2002
The proliferation of market places and trading methods is a striking feature of current equity markets. A stated goal of all the new trading arrangements is to reduce transactions costs. We investigate costs in one new market place, the crossing network.
Ødegaard, Bernt Arne, Næs, Randi
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Stress assessment and control measures for deformed tunnel-crossing pipeline section

open access: yesYou-qi chuyun
Objective It is common for long-distance oil and gas pipelines to traverse mountain tunnels. The sections of pipelines passing through tunnels are susceptible to significant deformation due to internal pressure and temperature effects during the ...
Chunbin QIU
doaj   +1 more source

Adaptive Management Planning Projects as Conflict Resolution Processes

open access: yesEcology and Society, 2006
Adaptive management planning projects use multiparty, multidisciplinary workshops and simulation modeling to facilitate dialogue, negotiation, and planning. However, they have been criticized as a poor medium for conflict resolution.
Greg Walkerden
doaj   +1 more source

Home - About - Disclaimer - Privacy