Results 141 to 150 of about 300,493 (300)

Genetic Gain and Inbreeding in Different Simulated Genomic Selection Schemes for Grain Yield and Oil Content in Safflower

open access: yesPlants
Safflower (Carthamus tinctorius L.) is a multipurpose minor crop consumed by developed and developing nations around the world with limited research funding and genetic resources.
Huanhuan Zhao   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Genetic diversity and distance among Iranian and European alfalfa (Medicago sativa L.) genotypes [PDF]

open access: yes, 2011
Alfalfa is the best known fodder crop with high ability of biological nitrogen fixation and drought tolerance in dry, Pannonian region of east Austria.
Ardakani, M.Reza   +5 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Future of Cydia pomonella Granulovirus in Biological Control of Codling Moth [PDF]

open access: yes, 2008
Resistance of codling moth against Cydia pomonella granulovirus (CpGV) products has alarmed growers, extension services, the CpGV producers and the scientific community.
Jehle, J. A.
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

CONTROLUL GENETIC AL MEIOZEI LA PLANTE

open access: yesStudia Universitatis Moldaviae: Stiinte reale si ale naturii, 2013
Meioza este un proces biologic fundamental al eucariotelor cu reproducere sexuată. În această lucrare vom revizui progresele realizate în ultimii ani pentru izolarea genelor meiotice la diferite specii de plante.
USM ADMIN
doaj  

International Collaboration in Crop Improvement Research: Current Status and Future Prospects [PDF]

open access: yes
Investments over the past 35 years have created a system of national and international research centers that has revolutionized the supply of improved cereal varieties to developing country farmers. The newly created scientific ability to exploit genetic
Pingali, Prabhu L., Traxler, Greg
core   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

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