Senataxin plays an essential role with DNA damage response proteins in meiotic recombination and gene silencing. [PDF]
Senataxin, mutated in the human genetic disorder ataxia with oculomotor apraxia type 2 (AOA2), plays an important role in maintaining genome integrity by coordination of transcription, DNA replication, and the DNA damage response.
Olivier J Becherel +12 more
doaj +1 more source
Widespread gene conversion in centromere cores. [PDF]
Centromeres are the most dynamic regions of the genome, yet they are typified by little or no crossing over, making it difficult to explain the origin of this diversity.
Jinghua Shi +5 more
doaj +1 more source
Meiotic recombination in Arabidopsis is catalysed by DMC1, with RAD51 playing a supporting role. [PDF]
Recombination establishes the chiasmata that physically link pairs of homologous chromosomes in meiosis, ensuring their balanced segregation at the first meiotic division and generating genetic variation.
Olivier Da Ines +5 more
doaj +1 more source
Genetic variability in soybean with resistance to cyst nematode and powdery mildew: impact of multi-parent crosses on recombination and genetic diversity [PDF]
The objective of this study was to analyze the genetic variability generated from two-way, four-way, and eight-way hybridizations in soybean, derived from parental lines contrasting in resistance to cyst nematode and powdery mildew.
F. R. S. Muniz +6 more
doaj +1 more source
Genome-Wide Association Study and Subsequent Exclusion of ATCAY as a Candidate Gene Involved in Equine Neuroaxonal Dystrophy Using Two Animal Models. [PDF]
Equine neuroaxonal dystrophy/equine degenerative myeloencephalopathy (eNAD/EDM) is an inherited neurodegenerative disorder of unknown etiology. Clinical signs of neurological deficits develop within the first year of life in vitamin E (vitE) deficient ...
Dahlgren, Anna R +6 more
core +1 more source
Inversions in the third chromosome of wild races of Drosophila pseudoobscura, and their use in the study of the history of the species [PDF]
Genetic studies showed several years ago that the third chromosomes of wild strains of Drosophila pseudoobscura often carry suppressors of crossing-over.
Dobzhansky, Th., Sturtevant, A. H.
core +1 more source
Regulated Proteolysis of MutSγ Controls Meiotic Crossing Over.
Crossover recombination is essential for accurate chromosome segregation during meiosis. The MutSγ complex, Msh4-Msh5, facilitates crossing over by binding and stabilizing nascent recombination intermediates. We show that these activities are governed by
Wei He +22 more
semanticscholar +1 more source
Variability of cell wall polysaccharides composition and hemicellulose enzymatic profile in an apple progeny [PDF]
The genetic variability of apple cell walls polysaccharides chemical composition and structure was assessed in a progeny of 141 individuals harvested over 2 years.
B. Quéméner +3 more
core +3 more sources
Comparative gene mapping in Arabidopsis lyrata chromosomes 1 and 2 and the corresponding A. thaliana chromosome 1: recombination rates, rearrangements and centromere location [PDF]
To add detail to the genetic map of Arabidopsis lyrata, and compare it with that of A. thaliana, we have developed many additional markers in the A. lyrata linkage groups, LG1 and LG2, corresponding to A. thaliana chromosome 1.
Charlesworth, D +4 more
core +1 more source
Meiotic crossing over ensures proper segregation of homologous chromosomes and generates genotypic diversity. Despite these functions, little is known about the genetic factors and population genetic forces involved in the evolution of recombination rate
Cara L. Brand +2 more
doaj +1 more source

