Results 131 to 140 of about 179,339 (238)

The rate of identical-by-descent segment sharing between close and distant relatives. [PDF]

HGG Adv
Williams AL.
europepmc   +1 more source

Advancing Precision Nutrition Through Multimodal Data and Artificial Intelligence

Advanced Science, EarlyView.
Individual responses to food vary dramatically, challenging traditional dietary advice. This review explores how the unique genetic makeup, gut microbiome, and brain activity shape host metabolic health. We examine how artificial intelligence integrates these multimodal data to predict individualized dietary needs, moving beyond one‐size‐fits‐all ...
Yuanqing Fu, Ke Zhang, Zelei Miao, Gaoyi Yang, Yujing Huang, Ju‐Sheng Zheng   +5 more
wiley   +1 more source

A note on rank-preserving structural failure time models to account for crossover. [PDF]

Clin Trials
Torres-Saavedra PA, Freidlin B, Jeong JH, Korn EL.   +3 more
europepmc   +1 more source

Machine Learning Driven Window Blinds Inspired Porous Carbon‐Based Flake for Ultra‐Broadband Electromagnetic Wave Absorption

Advanced Science, EarlyView.
Inspired by the regulation mechanism of window blinds, this study designs an electromagnetic wave‐absorbing metamaterial. By introducing the magneto‐electric coupling concept and integrating it with an artificial intelligence‐based data‐driven collaborative optimization strategy, the material optimizes impedance matching performance and enhances loss ...
Zhe Wang, Wanchong Li, Lu Feng, Zaiqing Yang, Shicheng Jin, Dongxu Zhao, Xiaoyong Wu, Yan Wang, Yu Mao, Jinsong Zhang   +9 more
wiley   +1 more source

Acceptability of Minimalist Shoes Compared With Balance-Enhancing Shoes in Older Women: Protocol for a Randomised Crossover Trial. [PDF]

J Foot Ankle Res
Nor Azhar A, Bergin SM, Munteanu SE, Menz HB.   +3 more
europepmc   +1 more source

ZSL Orchestrates Synaptonemal Complex Assembly as a Central Region Scaffold to Ensure Synapsis Fidelity and Crossover Control in Polyploid Meiosis

Advanced Science, EarlyView.
A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng, Shaochen Jia, Fei Cao, Cuiping Liu, Heshuang Zhang, Gang Xu, Jixin Zhuang, Yashi Zhang, Can Liu, Yuhang Zhao, Zilin Guo, Xinjie Yuan, Jiaqing Yang, Lei Chu, Bowei Cai, Hu Zhao, Chao Yang   +16 more
wiley   +1 more source

Sex differences in crossover interference in house mice. [PDF]

G3 (Bethesda)
Morgan AP.
europepmc   +1 more source

Multi‐Targeting Non‐Specific Genome Engineering in Bacteria

Advanced Science, EarlyView.
In this study, we provide the first case to use the multi‐targeting integrase (MTI) systems in bacteria and develop a host‐independent generalizable approach, MNGE (Multi‐targeting Non‐specific Genome Engineering), for multi‐copy and random integration of metabolic genes or pathways in both Gram‐positive and Gram‐negative bacteria, which will ...
Runze Sun, Ruixiang You, Yiwen Zhou, Huiyan He, Wenfang Wang, Xudong Qu, Yinhua Lu, Lei Li   +7 more
wiley   +1 more source

Kinesin‐Induced Buckling Reveals the Limits of Microtubule Self‐Repair

Advanced Science, EarlyView.
This study shows that kinesin‐driven buckling induces extensive microtubule lattice damage that often exceeds intrinsic self‐repair and leads to filament failure. While curvature, motor motility, and force individually cause limited damage, their combination overwhelms repair.
Shweta Nandakumar, Jonas Bosche, Mirko Wieczorek, Constantin Matteo Albrecht, Belinda König, Mona Grünewald, Ludger Santen, Stefan Diez, Reza Shaebani, Laura Schaedel   +9 more
wiley   +1 more source

Nasal negative pressure oscillatory therapy versus oscillatory positive expiratory pressure for airway clearance in patients with acute exacerbations of bronchiectasis (NNPO-BE): a multicentre, randomised, crossover non-inferiority trial protocol. [PDF]

Front Med (Lausanne)
Wang S, Zhou Z, Ma X, Yang Y, Lei J, Shiwei Q, Gao B, Wang P, Le M, Jiang S, Yang T.   +10 more
europepmc   +1 more source