Results 171 to 180 of about 174,425 (315)

DNA Nanostructure‐Templated Multivalency Enables Broad‐Spectrum Virus Inhibition

Advanced Science, EarlyView.
A honeycomb‐shaped DNA nanostructure is introduced that organizes nanobodies or aptamers into trimeric clusters mirroring the native hemagglutinin arrangement on influenza viruses. This geometry‐matched multivalency enhances binding avidity by up to 1000‐fold, resulting in robust, broad‐spectrum viral neutralization and a 30–55% improvement in host ...
Saurabh Umrao, Abhisek Dwivedy, Dhanush Gandavadi, Chi Chen, Lifeng Zhou, Jinwei Duan, Vineetha Mareddy, Ying Fang, Xing Wang   +8 more
wiley   +1 more source

Acute Effects of Ankle Bathing and Aerobic Exercise on Blood Pressure and Vascular Function in Older Adults: A Randomized Crossover Study

Ye Ji Choi, Min Jeong Cho, Kanokwan Bunsawat, Byul Kim, Hyun Jeong Kim, Sae Young Jae   +5 more
openalex   +2 more sources

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Acute blood biomarker responses to consensual sexual choking/strangulation in young adult women: a randomized crossover study. [PDF]

Front Glob Womens Health
Sweeney SH, Recht GO, Lima-Cooper G, Datta D, Buddenbaum CV, Day H, Buehler B, Huibregtse ME, Herbenick D, Kawata K.   +9 more
europepmc   +1 more source

Beneficial Effects of Consuming a Natural Zero Calorie Sweetener Preload Prior to Lunch on Energy Intake: A Double-blind Randomised Crossover Study (FS18-01-19)

, 2019
Nikoleta S. Stamataki, Rebecca Elliott, Shane McKie, John McLaughlin   +3 more
openalex   +1 more source

Population‐Based Multi‐Omics and Cohort Study Identifying Predictive Biomarkers and Therapeutic Targets for Psoriatic Disease

Advanced Science, EarlyView.
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu, Jialiang Luo, Haoyuan Qiu, Weijie Shao, Yueyang Lu, Meixuan Luo, Zhaofeng Lin, Yan Zhang, Libo Zhang, Hong Wang, Jia Zhou, Guangfeng Ruan, Peihua Cao, Daming Zuo   +13 more
wiley   +1 more source

The effect of nicotine delivery system on blood protease levels: a randomized crossover study. [PDF]

Sci Rep
Wilson AC, Leavens ELS, Covarrubias-Zambrano O, Lambart L, Bossmann SH, Nollen NL, Tarran R.   +6 more
europepmc   +1 more source

Effects of fine particulate matter from wildfire and non-wildfire sources on emergency-department visits in people who were housed and unhoused in San Diego County (CA, USA) during 2012–20: a time-stratified case–crossover study

Lara Schwarz, Andrew Nguyen, Emilie Schwarz, Edward M. Castillo, Jesse J. Brennan, Theodore C. Chan, Rosana Aguilera, Alexander Gershunov, Tarik Benmarhnia   +8 more
openalex   +1 more source

AI‐Optimized Vanadium Oxide Multilayers for More Than 20‐fold Enhancement in Bolometric Performance

Advanced Science, EarlyView.
Machine‐learning‐optimized WxV1‐xOy multilayer thin films with graded doping achieve a high TCR (7.3 % K−1), reduced hysteresis, and low noise under CMOS‐compatible growth conditions. This approach overcomes the long‐standing trade‐off in microbolometers between linear response and performance, offering a universal bolometric parameter greatly enhanced
Jin‐Hyun Choi, Hyoung‐Taek Lee, Jeonghoon Kim, Miju Park, Seungjoon Sun, Gye‐Hyeon Kim, Myung‐Ho Kwon, Hyeong‐Ryeol Park, Changhee Sohn   +8 more
wiley   +1 more source

Effect of Blue Covarine Toothpastes on Tooth Colour: A Randomised Crossover Study. [PDF]

Int Dent J
Zhang L, Joiner A, Gupta AK, Barili M, Platten S, McDonald MD, Luo W, Matheson JR.   +7 more
europepmc   +1 more source