Results 71 to 80 of about 294,375 (288)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Data and code for Core crosstalk in ordered imaging fibre bundles

open access: yes, 2020
Data and code for the paper: "Core crosstalk in ordered imaging fibre bundles" Parker, H, et al. (Accepted manuscript)
Stone, James   +4 more
core   +1 more source

Wide Color Gamut Time-Multiplexed Stereoscopic Display Based on Scanning Backlight Unit Utilizing Sectional Light Guide Plates

open access: yesIEEE Access, 2019
A time-multiplexed stereoscopic display with a wide color gamut is fabricated and introduced in this paper. It comprises a scanning backlight unit (SBLU), a 120Hz liquid crystal display (LCD) panel and a pair of LCD shutter glasses equipped with two ...
Bin Xu, Yuanqing Wang
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Modeling crosstalk effects in CNT bus architectures

open access: yes, 2007
Carbon nanotubes (CNTs) have been widely proposed as interconnect fabric for nano and very deep submicron (silicon-based) technologies due to their robustness to electromigration.
J. M. Cazeaux   +13 more
core   +1 more source

A novel dual-walled CNT bus architecture with reduced cross-coupling features [PDF]

open access: yes, 2006
Carbon Nano Tubes (CNTs) have been widely proposed as interconnect fabric for nano and very deep sub-micron (silicon-based) technologies due to their robustness to electromigration.
J. M. Cazeaux   +8 more
core   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Simulation and Optimization of Control Board Used in Electric Vehicle Drive System

open access: yesKongzhi Yu Xinxi Jishu, 2014
Based on a drive system control board of electric vehicle, modeling and simulation were performed for the EMC via Ansys simulation software, hence an improved design method was proposed.
FAN Zhuxia   +3 more
doaj  

Home - About - Disclaimer - Privacy