Results 51 to 60 of about 32,318 (255)

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

Advanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She, Rui Liu, Chen Fang, Shuyu Zhang, Yizhi Hu, Fei Guo, Yuhang Long, Mengzhen Ding, Haiyan Wu, Bokang Zhou, Zexin Yang, Ying Jiang, Jianzhong Sheng, Ling Gao, Hefeng Huang   +14 more
wiley   +1 more source

Comparative Evaluation of Fracture Toughness and Marginal Adaptation of PEEK and Cast Metal Crowns for Restoring Posterior Teeth with Endocrown and Richmond Crown: An In Vitro Study [PDF]

International Journal of Prosthodontics and Restorative Dentistry
Purpose: The purpose of this study was to evaluate and compare the fracture toughness and marginal adaptation of polyether ether ketone (PEEK) and cast metal crowns for restoring posterior teeth using the endocrown and Richmond crown techniques ...
Charnpreet Singh, Shefali Singla, Sunint Singh, Lalit Kumar, Komalpreet Kaur   +4 more
doaj   +1 more source

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

Advanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen, Xinkai Pu, Ruiyang Li, Yuezhou Wu, Qirong Zhou, Jian Wang, Yuxuan Qian, Fengjie Lu, Jian‐Yuan Zhao, Zhida Su, Jiacan Su, Xiaofeng Lian   +11 more
wiley   +1 more source

Redox‐Active NiOx‐Catalyzed Li+ Capture‐Extraction Strategy for tBP‐Free Spiro‐OMeTAD Enables Exceptional Damp‐Heat Stability in Perovskite Solar Cells

Advanced Science, EarlyView.
The redox‐active nature of NiOx enables ultrafast oxidative doping of spiro‐OMeTAD within seconds. Concurrently, NiOx‐Li+ coordination complexes formed during this redox process are selectively removed by filtration, effectively extracting residual Li+ ions from the film.
Yun Seop Shin, Minjin Kim, Jaehwi Lee, Chang Hyeon Yoon, Jongdeuk Seo, Gyeong‐Cheon Choi, Sujung Park, Min Jung Sung, Kyungnan Son, Sungjun Hong, Inyoung Jeong, Junseop Byeon, Yimhyun Jo, Dongmin Lee, Minseong Kim, Shinuk Cho, Ji‐Youn Seo, Jin Young Kim, Dong Suk Kim, SeJin Ahn   +19 more
wiley   +1 more source

A multi-center retrospective assessment of monolithic zirconia restorations on posterior teeth and implants.

Journal of Oral Research, 2019
Objective: the purpose of this multicenter retrospective study was to report on survival, success, and complication rates in monolithic zirconia restorations on teeth and implants.
Sandra AlTarawneh, Motasum Abu-Awwad, Salah Riyal, Rania Samara, Susan Hattar   +4 more
doaj   +1 more source

Synergistic Hydrogen‐Bonding and Covalent Crosslinking in Polybenzimidazole Membranes for Wide‐Temperature Anhydrous Fuel Cells

Advanced Science, EarlyView.
A dual‐network architecture combining a thermally reinforced hydrogen‐bonding matrix with an amine‐anhydride covalent framework was constructed in Tröger's Base (TB)‐functionalized polybenzimidazoles. This design yielded the TBAm‐PBI‐TB membrane with high acid uptake (469.5%), anhydrous conductivity (264.7 mS cm−1), and robust stability.
Junming Dai, Jianming Zhong, Jinpeng Luo, Yuxing Song, Fan Hu, Young Moo Lee, Yongbing Zhuang   +6 more
wiley   +1 more source

2D Metal‐Organic Frameworks for High‐Performance Solid‐State Electrolytes: A Comprehensive Review

Advanced Science, EarlyView.
In this review, we elucidate the intrinsic advantages, synthetic methodologies, structural characteristics, ion‐transport mechanisms and performance optimization strategies while highlighting representative material systems and applications of 2D MOFs for electrolyte applications.
Changchun Ai, Yuan Tian, Yilei Shu, Peng Hang, Wentao Li, Yiling Yao, Huijuan Guo, Qun Yi, Hongmei Dai   +8 more
wiley   +1 more source

A Metal‐Free Molecular Ferroelectric With Large Piezoelectricity and Its Porous Composite for Superior Output Power Density

Advanced Science, EarlyView.
Metal‐free molecular crystal [(CH3C6H10NH3)(18‐crown‐6)][ClO4] functions as a high‐performance molecular ferroelectric. Through strategic methylation of the cyclohexylamine unit, the compound achieves large spontaneous polarization and outstanding piezoelectric coefficients.
Nan Chen, Wenjuan Wei, Le Ye, Lingyu Wan, Yen Wei   +4 more
wiley   +1 more source

Materials and Methods for All-Ceramic Dental Restorations Using Computer-Aided Design (CAD) and Computer-Aided Manufacturing (CAM) Technologies—A Brief Review

Dentistry Journal
The materials used in dentistry for the fabrication of all-ceramic restorations have undergone great and rapid developments over the last two decades.
Nestor Washington Solís Pinargote, Oleg Yanushevich, Natella Krikheli, Anton Smirnov, Sergey Savilkin, Sergey N. Grigoriev, Pavel Peretyagin   +6 more
doaj   +1 more source