Results 81 to 90 of about 227,665 (340)

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

Exchanging Goods Using Valuable Money

, 2016
A group of people wishes to use money to exchange goods efficiently over several time periods. However, there are disadvantages to using any of the goods as money, and in addition fiat money issued in the form of notes or coins will be valueless in the ...
Howard, J. V.
core  

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Principles for Rigorous Design and Application of Synthetic Microbial Communities

Advanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang, Minyu Jing, Lihui Lyu, Li Nie, Xihui Xu, Ru Sun, Xiyuan Xu, Siyu Chen, Shuobing He, Yumeng Zhang, Ping Huang, Weijie Luo, Jiaojiao Liang, Guifeng Gao, Kunkun Fan, Teng Yang, Liyan Zhang, Xiao Fu, Sarah M. Allard, Jack A. Gilbert, Jiabao Zhang, Haiyan Chu   +21 more
wiley   +1 more source

Materials and Methods for All-Ceramic Dental Restorations Using Computer-Aided Design (CAD) and Computer-Aided Manufacturing (CAM) Technologies—A Brief Review

Dentistry Journal
The materials used in dentistry for the fabrication of all-ceramic restorations have undergone great and rapid developments over the last two decades.
Nestor Washington Solís Pinargote, Oleg Yanushevich, Natella Krikheli, Anton Smirnov, Sergey Savilkin, Sergey N. Grigoriev, Pavel Peretyagin   +6 more
doaj   +1 more source

Metal‐Organic Framework‐Based Supercapacitors: A Comprehensive Review

Advanced Science, EarlyView.
Overview of Metal‐Organic Frameworks (MOFs) derived electrode materials for supercapacitors. Illustration of redox reactions, conductivity enhancement, and structural stability during charge‐discharge cycling. Emphasis on synergistic effects due to surface area, porosity leading to improved electrochemical performance and energy storage efficiency ...
Swapnajit V. Mulik, Mrunal M. Patil, Sonali P. Sadavar, Sagar D. Delekar, Rajendra K. Bordia, Dillip K. Panda   +5 more
wiley   +1 more source

Evaluation of the Marginal Fit of Virgilite Based Lithium Disilicate Ceramic Crowns: An In-Vitro Comparative Study

Journal of Pharmacy and Bioallied Sciences
Background: Achieving optimal marginal fit is essential for the success of Virgilite Based Lithium Disilicate Ceramic crowns. Materials and Methods: In this in-vitro study, we compared the marginal fit of Virgilite Based Lithium Disilicate Ceramic crowns
Sherif El Sayed Sultan, Khaled Ahmad Saud Alsabilah, Bader Mahali Alharbi, Addulrhman Fahad Alnaser   +3 more
doaj   +1 more source

Reprogramming M2b Macrophages via GPX1 Activation by Selenium Nanoparticles Attenuates Lupus Nephritis

Advanced Science, EarlyView.
SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...
Haoran Lv, Guanning Huang, Hongyu Li, Hanzhi Liang, Huajing Peng, Kefei Wu, Wenfang Chen, Dandan Zhang, Kexin Ma, Yufei Du, Siweier Luo, Yi Zhou, Haiping Mao, Wei Chen, Tianfeng Chen, Yiming Zhou, Qinghua Liu   +16 more
wiley   +1 more source

Effect of axial groove and resin luting cements on the retention of complete cast metal crowns

Dental Research Journal, 2009
Background : The design of the tooth preparation and the cementing medium are important consid-erations in the retention of crowns and fixed partial dentures.
K Rajkumar, Aruna M Bhat, D Krishna Prasad, Chetan Hegde, Manoj Shetty, N Sridhar Shetty   +5 more
doaj  

Orthodontic management of amelogenesis imperfecta: A case report

Clinical Case Reports
Key Clinical Message Amelogenesis imperfecta (AI) is a rare developmental anomaly characterized by poorly developed or absent tooth enamel, which complicates orthodontic treatment due to weak enamel‐bracket bond strength.
Kanistika Jha, Manoj Adhikari, Suraksha Shrestha, Anisha Pandey   +3 more
doaj   +1 more source