Results 191 to 200 of about 14,964 (269)

What Happens After Menopause (WHAM)? A Progress Report of a Prospective Controlled Study of Women After Pre‐Menopausal Risk‐Reducing Bilateral Salpingo‐Oophorectomy

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Surgical menopause, the removal of both ovaries prior to natural menopause, may impact short‐and long‐term physical and emotional health. An increasingly common cause of surgical menopause is risk‐reducing salpingo‐oophorectomy (RRSO) in those at high inherited risk of ovarian cancer.
Sarah A. L. Price, Pauline M. Maki, Samar R. El Khoudary, Alison Brand, Rakibul M. Islam, Susan M. Domchek, Hadine Joffe, Gita D. Mishra, Katrina M. Moss, Fiona C. Baker, Sabine Braat, John D. Wark, Martha Hickey   +12 more
wiley   +1 more source

Implications of Changing the Diagnostic Criteria for Gestational Diabetes Mellitus (CDC4G): A Healthcare Cost Analysis Alongside a Stepped Wedge Cluster Randomised Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To estimate the effect on healthcare resource use after introducing the World Health Organization diagnostic criteria (WHO‐2013) for gestational diabetes mellitus (GDM) compared to former criteria in Sweden (SWE‐GDM). Design A cost‐analysis alongside the Changing Diagnostic Criteria for Gestational Diabetes (CDC4G) randomised ...
Maryam de Brun, Naimi Johansson, David Simmons, Scott Montgomery, Kerstin Berntorp, Stefan Jansson, Ulla‐Britt Wennerholm, Anna‐Karin Wikström, Helena Strevens, Fredrik Ahlsson, Verena Sengpiel, Elisabeth Storck‐Lindholm, Martina Persson, Kerstin Petersson, Carina Ursing, Linda Ryen, Helena Backman   +16 more
wiley   +1 more source

Increased risk of type I errors for detecting heterogeneity of treatment effects in cluster-randomized trials using mixed-effect models. [PDF]

BMC Med Res Methodol
Hyun N, Idu AE, Cook AJ, Bobb JF.
europepmc   +1 more source

Estimating the Carbon Footprint of External Beam Radiotherapy: Should This Be a Concern for LMICs?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Purpose This study aims to estimate the carbon footprint associated with external beam radiotherapy in a low‐ and middle‐income country (LMIC) context, specifically at the Uganda Cancer Institute (UCI), and to evaluate whether sustainability should be a priority alongside treatment access in such radiation therapy settings.
Afua A. Yorke, Komakech Ignatius, John L. Schreiner, Tomas Kron   +3 more
wiley   +1 more source

Multidomain predictors of long-term work disability in late survivorship after head and neck cancer. [PDF]

Support Care Cancer
Ivanova A, Amdal CD, Kvalem IL, Reme SE.
europepmc   +1 more source

Voice of Asia: Provision of Patient‐Centered Care in Oral Cavity Cancer: A Qualitative Study With Patients, Caregivers, and Healthcare Professionals in Five Asia‐Pacific Regions

Asia-Pacific Journal of Clinical Oncology, EarlyView.
The study identified key barriers to optimal patient‐centered care, including delayed diagnosis due to awareness and stigma‐related barriers among patients and caregivers, and opportunities to enhance multidisciplinary coordination. Resource limitations impacted nursing and psychosocial support, while access to support care varied across regions.
Edwin Pun Hui, Puma Sundaresan, Hye Ryun Kim, Khoi Tuan Nguyen, Tracey E Nicholls, Hai‐Ling Teng, Yu‐Chung Li, Ying Jie Yew, Regina Gowindah, Con Stylianou, Pei‐Jen Lou   +10 more
wiley   +1 more source

Characterisation of between-cluster heterogeneity in malaria cluster randomised trials to inform future sample size calculations. [PDF]

Nat Commun
Biggs J, Challenger JD, Dee D, Elobolobo E, Chaccour C, Saute F, Staedke SG, Vilakati S, Chung JB, Hsiang MS, Dabira ED, Erhart A, D'Alessandro U, Tripura R, Peto TJ, Von Seidlein L, Mukaka M, Mosha J, Protopopoff N, Accrombessi M, Hayes R, Churcher TS, Cook J.   +22 more
europepmc   +1 more source

Impact of Metformin and Diabetes on Tumor Response to Total Neoadjuvant Therapy in Advanced Rectal Cancer: A Multicenter Retrospective Cohort Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski, Mahima Raju, Tracy Fitzsimmons, Ishraq Murshed, Timothy J. Price, Michael Penniment, Sudarsha Selva‐Nayagam, Tarik Sammour   +7 more
wiley   +1 more source

What Is a Stepped-Wedge Cluster Randomized Trial? [PDF]

JAMA Intern Med
Li F, Wang B, Heagerty PJ.
europepmc   +1 more source

Real‐world outcomes of aflibercept 8 mg in patients previously treated for neovascular age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate visual, anatomical and safety outcomes of aflibercept 8 mg in previously treated patients with neovascular age‐related macular degeneration (nAMD). Methods This retrospective study included nAMD patients switched to aflibercept 8 mg from prior anti‐VEGF therapies at Sahlgrenska University Hospital between February 2024 and ...
Imadeddin Abu Ishkheidem, Esra Inci, Martin Breimer, Sofia Töyrä Silfverswärd, Madeleine Zetterberg, Marita Andersson Grönlund   +5 more
wiley   +1 more source