Results 41 to 50 of about 14,964 (269)

CRT only or CRT plus ICD? [PDF]

European Heart Journal Supplements, 2004
Aims Cardiac resynchronization therapy (CRT) has been shown in several clinical trials to improve symptoms and exercise capacity in patients with advanced heart failure. The first clinical trials of CRT-D devices were based on populations who already met a standard indication for implantable cardioverter defibrillator (ICD) therapy.
openaire   +1 more source

Ferritin‐Doped Nanoparticles Triggered Tumor‐Specific Darkening for Enhanced Photothermal Tumor Ablation and Immune Activation

Advanced Healthcare Materials, EarlyView.
Ferritin‐doped hybrid nanoparticles triggered accurate tumor‐specific hemorrhage for enhanced in situ photothermal therapy and evoked anti‐tumor immunity. Notably, HFn/GA‐Fe specifically induced tumor hemorrhage 12 h after intravenous injection, resulting in visible color darkening. Through photoacoustic imaging, tumor vessels could be clearly observed
Haidong Zha, Xiao Liang, Long Xi, Jiamao Chen, Wenzhao Zhong, Zhen Yuan, Meng Xu, Ying Zheng   +7 more
wiley   +1 more source

Incidence of asymptomatic catheter-related thrombosis in intensive care unit patients: a prospective cohort study

Annals of Intensive Care, 2023
Background Catheter-related thrombosis (CRT) incidence, rate, and risk factors vary in literature due to differences in populations, catheters, diagnostic methods, and statistical approaches.
Chiara Abbruzzese, Amedeo Guzzardella, Dario Consonni, Gloria Turconi, Claudia Bonetti, Matteo Brioni, Mauro Panigada, Giacomo Grasselli   +7 more
doaj   +1 more source

Cost-effectiveness analysis of 3-D computerized tomography colonography versus optical colonoscopy for imaging symptomatic gastroenterology patients.

, 2013
BACKGROUND: When symptomatic gastroenterology patients have an indication for colonic imaging, clinicians have a choice between optical colonoscopy (OC) and computerized tomography colonography with three-dimensional reconstruction (3-D CTC).
A Briggs, A Graser, A Sweet, AI Neugut, B Bressler, B Bressler, B Hofstad, B Hofstad, BCSP Nhs, BP Mulhall, C Dukes, C Hassan, C Hassan, CD Johnson, D Burling, D Lee, DA Johnson, Department of Health and Human Services, DG Fryback, DH Kim, DJ Brenner, DK Rex, DK Rex, DK Rex, EC Obusez, F Loeve, HE Knoernschild, J Dowie, JA DiSario, James Bell, JJ Gonvers, L Ries, LM Almond, M Bose, M Chaparro, M Drummond, M McHugh, Manuel Gomes, ME Zalis, NICE, NICE, NICE, NM Gatto, Owen Epstein, P Consolo, P Tappenden, P Wylie, PB Cotton, Peter Wylie, PJ Pickhardt, PJ Pickhardt, PJ Pickhardt, PJ Pickhardt, PJ Pickhardt, PJ Pickhardt, PJ Pickhardt, RE Gelder Van, RE Schoen, RM Ness, Robert W. Aldridge, S Halligan, S Halligan, S Vijan, SJ Winawer, T Vanni, TR Levin, WS Atkin, WS Atkin   +67 more
core   +1 more source

A Population of Short-Period Variable Quasars from PTF as Supermassive Black Hole Binary Candidates [PDF]

, 2016
Supermassive black hole binaries (SMBHBs) at sub-parsec separations should be common in galactic nuclei, as a result of frequent galaxy mergers. Hydrodynamical simulations of circumbinary discs predict strong periodic modulation of the mass accretion ...
Bartos, I., Bellm, E. C., Charisi, M., Graham, M. J., Haiman, Z., Laher, R. R., Marka, S., Price-Whelan, A. M.   +7 more
core   +2 more sources

The risk of ventricular arrhythmias in a Dutch CRT population: CRT-defibrillator versus CRT-pacemaker [PDF]

Netherlands Heart Journal, 2016
Patients eligible for cardiac resynchronisation therapy (CRT) have an indication for primary prophylactic implantable cardioverter defibrillator (ICD) therapy. However, response to CRT might influence processes involved in arrhythmogenesis and therefore change the necessity of ICD therapy in certain patients.In 202 CRT-defibrillator patients, the ...
Ter Horst, I A H, van 't Sant, J, Wijers, S C, Vos, M A, Cramer, M J, Meine, M   +5 more
openaire   +3 more sources

Cold Atmospheric Plasma‐Activated Decellularized Extracellular Matrix Gel as a Tumor‐Infiltrating Immunoactivation Platform for Post‐Surgical Cancer Immunotherapy

Advanced Materials, EarlyView.
An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang, Mo Chen, Yueyang Deng, Tianqin Ning, Tianwen Luo, Guojun Chen   +5 more
wiley   +1 more source

Pre-existing Functional Heterogeneity of Tumorigenic Compartment as the Origin of Chemoresistance in Pancreatic Tumors

Cell Reports, 2019
Summary: Adaptive drug-resistance mechanisms allow human tumors to evade treatment through selection and expansion of treatment-resistant clones. Here, studying clonal evolution of tumor cells derived from human pancreatic tumors, we demonstrate that in ...
Sahil Seth, Chieh-Yuan Li, I-Lin Ho, Denise Corti, Sara Loponte, Luigi Sapio, Edoardo Del Poggetto, Er-Yen Yen, Frederick Scott Robinson, Michael Peoples, Tatiana Karpinets, Angela Kay Deem, Tapsi Kumar, Xingzhi Song, Shan Jiang, Ya’an Kang, Jason Fleming, Michael Kim, Jianhua Zhang, Anirban Maitra, Timothy Paul Heffernan, Virginia Giuliani, Giannicola Genovese, Andrew Futreal, Giulio Francesco Draetta, Alessandro Carugo, Andrea Viale   +26 more
doaj   +1 more source

Ethical Issues in the Design and Conduct of Pragmatic Cluster Randomized Trials in Hemodialysis Care: An Interview Study With Key Stakeholders

Canadian Journal of Kidney Health and Disease, 2020
Background: Pragmatic cluster randomized trials (CRTs) offer an opportunity to improve health care by answering important questions about the comparative effectiveness of treatments using a trial design that can be embedded in routine care.
Stuart G. Nicholls, Kelly Carroll, Charles Weijer, Cory E. Goldstein, Jamie Brehaut, Manish M. Sood, Ahmed Al-Jaishi, Erika Basile, Jeremy M. Grimshaw, Amit X. Garg, Monica Taljaard   +10 more
doaj   +1 more source

Remote‐Controllable Immune‐Priming Spot Formation Via Nanocomplexed Hydrogel‐Assisted Histotripsy: Immunoasis

Advanced Materials, EarlyView.
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim, Wonseok Choi, Yurim Kim, Hyeongmin Kim, Gu Won Jeong, Hyewon Park, Inchan Youn, Yoon Park, Sungmin Han, Young‐Min Kim   +9 more
wiley   +1 more source