Results 41 to 50 of about 133,466 (244)

Injury Risk Estimation Expertise Assessing the ACL Injury Risk Estimation Quiz [PDF]

, 2015
Background: Available methods for screening anterior cruciate ligament (ACL) injury risk are effective but limited in application as they generally rely on expensive and time-consuming biomechanical movement analysis.
Ward , P., Wallace, Sean J., Durocher, John, Petushek, E., Petuchek, Erich J., John J. Durocher, Wallace, Sean, Myer, Gregory D., Gregory D. Myer, Edward T. Cokely, Ward, Paul, Cokely, E., Petushek, Erich J., Paul Ward, Cokely, Edward T., Erich J. Petushek, Sean J. Wallace, Myer , G., Wallace , S., Cokely, Edward, Durocher, J., Durocher, John J, Durocher, John J.   +22 more
core   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Periprosthetic total knee fracture after remote reconstruction of the anterior cruciate ligament: a case report

Journal of Medical Case Reports, 2017
Background Distal femoral fracture is a rare, but significant, postoperative complication of anterior cruciate ligament reconstruction. However, there has not been a reported case of periprosthetic total knee arthroplasty fracture associated with a ...
Sahil Kooner, Eric Gibson, Marcia Clark
doaj   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source

Outcomes of Initial Nonoperative Management of Partial Anterior Cruciate Ligament Tears in Pediatric Patient

Journal of the Pediatric Orthopaedic Society of North America
Background: Partial anterior cruciate ligament (pACL) injuries are a challenging clinical problem without reliable diagnostic criteria and scant data on outcomes.
Megan M. Hannon, MD, Emily Chang, BA, Nicholas Sullivan, BS, Patricia E. Miller, MS, Melissa A. Christino, MD, Mininder S. Kocher, MD, MPH, William P. Meehan, III, MD   +6 more
doaj   +1 more source

Reverse Segond fracture and associated knee injuries: A case report and review of 13 published cases

Acta Orthopaedica et Traumatologica Turcica, 2016
Reverse Segond fracture is originally described as an indirect radiographic clue for a specific injury complex of the knee joint that includes posterior cruciate ligament (PCL) rupture and medial meniscal tear.
Ozkan Kose, Selahattin Ozyurek, Adil Turan, Ferhat Guler   +3 more
doaj   +1 more source

Nuclear Translocation of PFKFB3 Promotes Disuse‐Induced Muscle Atrophy via Scaffolding Nedd4‐Mediated JunB Ubiquitination

Advanced Science, EarlyView.
Disuse‐induced muscle atrophy is driven by a non‐metabolic, nuclear function of the enzyme PFKFB3. Acting as a scaffold, PFKFB3 facilitates Nedd4‐mediated ubiquitination and degradation of the anti‐atrophy transcription factor JunB. Inhibiting this novel PFKFB3–Nedd4–JunB signaling axis stabilizes JunB and alleviates muscle wasting, revealing a highly ...
Mengjun Ma, Yinliang Liu, Wangchang Wu, Biao Yang, Jiahao Zhuang, Haoye Yu, Rujia Mi, Yixuan Lu, Wen Yang, Hanting Yi, Chenglong Yuan, Yinfeng Gu, Hongyu Li   +12 more
wiley   +1 more source

Commercially Available Guides Overestimate Socket Length During Anterior and Posterior Cruciate Ligament Socket Retrograde Drilling

Arthroscopy, Sports Medicine, and Rehabilitation
Purpose: To objectively assess the accuracy of socket measurements taken during cruciate ligament reconstruction using a retrograde reaming technique. Methods: Six complete knee sawbone specimens were used to ream anterior and posterior cruciate ligament
Emily R. McDermott, M.D., Michael Proffitt, Ph.D., Clayton W. Nuelle, M.D., Bjorn Christian Balldin, M.D.   +3 more
doaj   +1 more source

Etiopathogenesis of Canine Cruciate Ligament Disease: A Scoping Review

Animals, 2023
The spontaneous rupture of the cranial cruciate ligament in dogs remains a pathoetiologic puzzle. Despite much progress in research over the past years, the systemic and local mechanisms leading to ligament degeneration and structural failure remain ...
Gert W. Niebauer, Brunella Restucci
doaj   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source