Results 91 to 100 of about 40,289 (297)

cruel

open access: yes, 1964
cruel aI did not grudge Pugsley the drink, after his yarn; but it was a cruel waste of good liquor to give it to those common fishermen.PRINTED ITEM DNE-cit W. J.

core  

Ablation‐Immune Thermal Armor Via Microstructural‐Compatibility Design for Extreme Thermal Conditions

open access: yesAdvanced Science, EarlyView.
This study unveils a microstructural‐compatibility design strategy that integrates reactive melt infiltration with plasma spraying to fabricate carbon fiber‐reinforced ZrC‐SiC composites. The deliberate incorporation of SiC into the ZrC coating releases heat accumulation, suppresses detrimental lamellar ZrO2 formation, and reduces residual stress. This
Hongkang Ou   +6 more
wiley   +1 more source

The Literary Sad Girl: Female Disaffect and Passive Dissent in 21st-Century Anglophone Fiction

open access: yesC21 Literature: Journal of 21st-century Writings
Referred to as ‘the sad girl’ in popular discourse, depictions of disaffected, inactive women increasingly pervade 21st-century literature, particularly female-authored Anglophone narratives.
Dilâra Yilmaz
doaj   +2 more sources

cruel

open access: yes, 1977
cruel aA cruel lot of it was taken to Bonne Bay and shipped all up and down the coast.PRINTED ITEM [fresh meat]W Kirwin 2/77 JH 2/77Used I and SupUsed I and Sup2Not UsedSOME, WONDERFULChecked by Jordyn Hughes on Wed 29 Jun ...

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An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

open access: yesAdvanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng   +8 more
wiley   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

open access: yesAdvanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li   +19 more
wiley   +1 more source

When Care Becomes Cruel

open access: yesPhilosophical Inquiry in Education
Drawing on our empirical study engaging focus groups of highly experienced educators and stakeholders (n=12) in Ontario, Canada, we examine the cruel refiguration of educational worker care under neoliberalism in public education.
Lana Parker, Holt Stuart-Hitchcox
doaj  

cruel

open access: yes, 1978
cruelsand where de water run deep! 1924 ENGLAND 257 An' I know one cap'n, too, as runs a store; an' one year when de men was paid off de swiler, he took a canvas bag an' stood on de w'arf an' as de men come off, he collected ahl as was owed him.

core  

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

open access: yesAdvanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu   +12 more
wiley   +1 more source

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