Results 41 to 50 of about 3,603 (259)

COVID-19 and the global cruise ship industry: potential recovery and reformation pathways

Bulletin of Geography. Socio-Economic Series, 2022
The cruise ship industry was one of the fastest growing subsectors of the tourism industry before the advent of COVID-19. This paper examines the prospects and recovery of the cruise ship industry from the devastating impacts of COVID-19 on the industry.
David Chikodzi, Godwell Nhamo, Kaitano Dube   +2 more
doaj   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

Environmental Sustainability in the Cruise Industry

Interdisciplinary Journal of Research and Development, 2022
Cruise shipping is currently one of the fastest growing segments in the tourism sector and creates a significant environmental impact. The aims of this study are a) to investigate what are the main environmental issues faced by the cruise ships and which measures are taken or foreseen to address the problems, b) to explore the passengers’ attitudes ...
Anna Maria Kotrikla, Evangelia Chortatsiani   +1 more
openaire   +1 more source

A social network analysis of interconnections among cruise ports

Asian Journal of Shipping and Logistics, 2021
Despite the dominance of the Caribbean as the leading cruise destination in the world, research that focuses on the network of cruise ports in the region is limited.
Uriel Armando Lopez Rodriguez, Sung-Hoon Park, Dong-Myung Kim, Gi-Tae Yeo   +3 more
doaj   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Resource allocation and growth strategies in a multi‐plant firm: Kanegafuchi Spinners in the early 20th century

Strategic Management Journal, EarlyView., 2023
Abstract Research Summary Using detailed plant‐ and individual‐level data from a major Japanese cotton spinning company in the early 20th century, we examine the within‐firm allocation of skilled human capital in conjunction with investment in physical capital, accompanying the firm's evolving strategic priorities.
Shotaro Yamaguchi, Serguey Braguinsky, Tetsuji Okazaki, Takenobu Yuki   +3 more
wiley   +1 more source

Le tourisme de croisière dans l’espace caribéen : évolutions récentes et enjeux de développement

Études Caribéennes, 2009
The Caribbean Sea is emblematic of the cruise, it is known for its international routes, scenic postcards touting the charms of the region. The analysis of the cruise industry will highlight some limits and contradictions of current development patterns.
Olivier Dehoorne, Christelle Murat, Nathalie Petit-Charles   +2 more
doaj   +1 more source

A C‐Nucleoside Analogue of Cordycepin With High Metabolic Stability and Potent Anti‐Psoriatic Activity via Microneedle Delivery

Advanced Science, EarlyView.
This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan, Xinyue Shao, Yuanchen Zhong, Xujie Sun, Lixuan Yin, Zongyan He, Tianqun Lang, Yuanchao Xie   +7 more
wiley   +1 more source

Customer perceptions of COVID-19 countermeasures on passenger ships during the pandemic

Transportation Research Interdisciplinary Perspectives, 2022
The COVID-19 pandemic devastated substantial portions of the tourism industry; the cruise industry particularly suffered from negative publicity as the virus spread rapidly on cruise ships.
Johnny Långstedt, Jonas Spohr, Magnus Hellström, Anastasia Tsvetkova, Erik Niemelä, Joakim Sjöblom, John E. Eriksson, Kim Wikström   +7 more
doaj   +1 more source

Five Issues of Artificial Intelligence in Science: Sailing the Ship of Theseus

Annals of Neurology, EarlyView.
Artificial intelligence (AI) is becoming part of the working infrastructure of academic medicine. Because grants convert scientific ideas into protected time, infrastructure, and institutional priority, they provide a revealing test case for AI's effects on biomedicine. Five issues are emerging: language, agency, review, doership, and identity.
S. Thomas Carmichael
wiley   +1 more source