Results 81 to 90 of about 13,767,591 (297)

UBE3A Dosage Imbalance as a Molecular Framework Linking Angelman Syndrome and Dup15q‐Associated Autism Phenotypes

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT UBE3A is a dosage‐sensitive HECT E3 ubiquitin ligase whose neuronal expression is shaped by genomic imprinting at the 15q11.2‐q13 locus. Opposite directions of UBE3A dosage imbalance contribute to distinct neurodevelopmental phenotypes: loss of maternal UBE3A underlies Angelman syndrome, whereas maternally derived 15q11.2‐q13 copy‐number gains,
Ruslan Kurmashev
wiley   +1 more source

Five Issues of Artificial Intelligence in Science: Sailing the Ship of Theseus

Annals of Neurology, EarlyView.
Artificial intelligence (AI) is becoming part of the working infrastructure of academic medicine. Because grants convert scientific ideas into protected time, infrastructure, and institutional priority, they provide a revealing test case for AI's effects on biomedicine. Five issues are emerging: language, agency, review, doership, and identity.
S. Thomas Carmichael
wiley   +1 more source

Exploring the cranial morphology and possible convergences of Triassic non‐crocodylomorph pseudosuchians (Archosauria: Pseudosuchia) with other sauropsids through linear morphometrics

The Anatomical Record, EarlyView.
Abstract Triassic pseudosuchians had highly diversified cranial morphologies. These archosaurs occupied diverse ecological roles, ranging from terrestrial predators and herbivores to semiaquatic ambush predators and possible waders. Here, we apply linear cranial morphometrics to assess possible convergences with other sauropsids from the clades ...
Rafael Terras, Rodrigo Temp Müller, Leonardo Kerber, Mirian Carbonera   +3 more
wiley   +1 more source

Scanning Parametric Sediment Echosounder as Tool for Underwater Archaeological Prospection

Archaeological Prospection, EarlyView.
ABSTRACT Underwater cultural heritage 3D prospection techniques, especially for remains that are partly buried in the ground, are only very rarely available and often can only be applied with considerable technical effort. To overcome this limitation, we evaluate a methodological adaption of widely used and available single channel parametric sediment ...
Dennis Wilken, Philipp Held, Jacob Geersen, Marcel Bradtmöller, Peter Feldens, Jens Schneider v. Deimling   +5 more
wiley   +1 more source

CARINA alkalinity data in the Atlantic Ocean [PDF]

Earth System Science Data, 2009
Data on carbon and carbon-relevant hydrographic and hydrochemical parameters from previously non-publicly available cruise data sets in the Arctic, Atlantic and Southern Ocean have been retrieved and merged to a new database: CARINA (CARbon IN the ...
A. Velo, F. F. Perez, P. Brown, T. Tanhua, U. Schuster, R. M. Key   +5 more
doaj  

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome

Arthritis &Rheumatology, EarlyView.
Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source

The life and legacy of Dr. Carlton G. Smith

Anatomical Sciences Education, EarlyView.
Abstract Carlton George Smith, M.Sc., M.D., Ph.D., R.C.N.V.R. (1905–2003) was a Canadian anatomist and professor at the University of Toronto. He was highly regarded as an outstanding teacher, cutting‐edge neuroscience researcher, and accomplished author. Dr. Smith became a member of the AAA in 1938 and joined the prestigious Cajal Club in 1950.
Mikaela L. Stiver, Anne M. R. Agur
wiley   +1 more source

Measurements of the partial pressure of CO2 in the air and surface sea water on board the icebreaker SHIRASE

Antarctic Record, 1997
With a newly developed automatic measurement system, the partial pressure of CO_2 in the surface sea water and lower troposphere were continuously monitored on board the icebreaker SHIRASE between Japan and Antarctica from November 1987 to March 1992 as ...
Gen Hashida, Takakiyo Nakazawa, Shuhji Aoki, Shohei Murayama, Takashi Yamanouchi, Masayuki Tanaka, Akira Shimizu, Masahiko Hayashi, Kunimoto Iwai   +8 more
doaj   +1 more source

The human foundations of anatomy at The University of Sydney: One hundred and one years of body procurement

Anatomical Sciences Education, EarlyView.
Abstract Body procurement at The University of Sydney has a long history. Anatomy legislation (1881 Anatomy Act) modeled on the British Anatomy Act 1832 legalized procurement of unclaimed bodies from public institutions for anatomical dissection at licensed Schools of Anatomy, effectively conferring the University of Sydney an exclusive license until ...
Rebekah A. Jenkin, Kevin A. Keay
wiley   +1 more source

CARINA: nutrient data in the Atlantic Ocean [PDF]

Earth System Science Data, 2009
Data on carbon and carbon-relevant hydrographic and hydrochemical parameters from previously non-publicly available cruise data sets in the Arctic, Atlantic and Southern Ocean have been retrieved and merged to a new database: CARINA (CARbon IN the ...
T. Tanhua, P. J. Brown, R. M. Key
doaj