Results 171 to 180 of about 36,112 (286)

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

Multifunctional Gelatin‐Based Smart Films Integrating Thermochromic Encryption, Temperature‐Regulated Photothermal Management, Reprocessability, and Biodegradability for Sustainable Applications

Advanced Science, EarlyView.
Multifunctional gelatin films synergizing thermochromic encryption, self‐regulating photothermal management, and closed‐loop recyclability offer sustainable solutions for intelligent packaging. ABSTRACT Multifunctional gelatin‐based smart films are engineered by incorporating hyperbranched polyglycerol (HBPG) as a plasticizer, dialdehyde β‐cyclodextrin
Yuehong Zhang, Chen Yang, Langlang Dai, Leipeng Liu, Vijay Kumar Thakur   +4 more
wiley   +1 more source

Hydrogen‐Bonding Networks Enabled by Trace Water for Morphological Design in Ternary Organic Solar Cells

Advanced Science, EarlyView.
Trace water transforms from an impurity to a design handle for ternary organic solar cells. During solvent evaporation, minimal amounts organize transient hydrogen‐bonding networks that steer component migration and set the morphology. The mechanism enables reproducible morphology locking and identifies a practical co‐solvent threshold near H2O:CF = 0 ...
Yue Ren, Ming‐Yue Sui, Yun Geng, Rui‐Cheng Qin, Ming‐Yang Li, Guang‐Yan Sun, Xin Xu   +6 more
wiley   +1 more source

Neocolonialism and science diplomacy: lessons learned from the field and the way forward. [PDF]

Front Public Health
Dajani R, Bayoumi R, Flowe H, Rockowitz S, Stevens L, Awad A.   +5 more
europepmc   +1 more source

Non-destructive insect metabarcoding for surveillance and biosecurity in citrus orchards: recording the good, the bad and the psyllids. [PDF]

PeerJ, 2023
Martoni F, Smith R, Piper AM, Lye J, Trollip C, Rodoni BC, Blacket MJ.   +6 more
europepmc   +1 more source

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

Gram‐Scale Synthesis of Hafnium‐Rich Carbon Dots for Preclinical Computed Tomography Imaging Across Various Systems

Advanced Science, EarlyView.
Hafnium (Hf)‐rich carbon dots (Hf‐rCDs) with high metal content (40.7%) and robust batch production capacity (>2 g per batch) are synthesized via a facile air‐assisted pyrolysis method. In vivo CT imaging demonstrates outstanding performance of Hf‐rCDs across multiple physiological systems and enables high‐resolution visualization of swine cervical ...
Shuo Li, Hengrui Wu, Jianqi Deng, Qiyu Sun, Yuping Zhang, Cai Zhang, Jinbin Pan, Dingbin Liu, Xuejun Zhang, Quan Zou, Xiaoyuan Chen, Shao‐Kai Sun   +11 more
wiley   +1 more source

The Unique <i>Liber Sermonum</i> of Martin of León (c.1130-1203): The Third Crusade, Popular Preaching and the Liturgical Front. [PDF]

J Mediev Hist
Marx A.
europepmc   +1 more source

McAuliffe-Shepard Aerospacefest to Feature UNH-Built Satellite [PDF]

, 2015
Sims, David
core   +1 more source

NIR Light‐Driven Photocatalytic Antibacterial Hydrogels for Synergistic MRSA Biofilm Eradication and Wound Regeneration

Advanced Science, EarlyView.
The nanohybrid hydrogel (Fe‐BOS@C/H Gel) is composed of Fe‐Bi2O2‐XS (Fe‐BOS) photocatalysts and CS‐ADH/OHA (C/H) hydrogel. Fe‐BOS photocatalysts achieve near‐infrared (NIR) light‐driven antibacterial photocatalytic/mild photothermal therapy (APCT/MPTT), effectively eliminating methicillin‐resistant Staphylococcus aureus (MRSA) biofilms. The degradation
Dong Mo, Yujia Wei, Meng Pan, Wen Chen, Yun Yang, Kang Li, Xicheng Li, Jianan Li, Qingya Liu, Hanzi Deng, Mei Zhu, Zhenpeng Zhang, Zhaolin Xiao, Zhiyong Qian   +13 more
wiley   +1 more source