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Crush injury and crush syndrome: a comprehensive review [PDF]
EFORT Open ReviewsCrush injury arises from prolonged external force on soft tissues, resulting in muscle necrosis and systemic manifestations known as crush syndrome. Pathophysiology involves ischemia, reperfusion injury and the release of toxic metabolites, which lead to
Vasileios S Akrivos +4 more
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Evaluation methods of a rat sciatic nerve crush injury model
Journal of Integrative Neuroscience, 2022 Background: The rat sciatic nerve crush injury model is one of the most commonly used models to research peripheral nerve injury (PNI), however, the evaluation of the model preparation lacks exact standards.
Yun An +4 more
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Application of Human Epineural Patch (hEP) as a Novel Strategy for Nerve Protection and Enhancement of Regeneration After Nerve Crush Injury [PDF]
BiomedicinesBackground: Numerous experimental studies aim to improve outcomes of peripheral nerve repair following trauma. This study evaluates the efficacy of the human epineural patch (hEP) compared to the human amniotic membrane (hAM) in promoting nerve ...
Katarzyna Kozlowska +6 more
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Biomolecules, 2022 Objective: To develop a standardized model of stretch–crush sciatic nerve injury in mice, and to compare outcomes of crush and novel stretch–crush injuries using standard manual gait and sensory assays, and compare them to both semi-automated as well as ...
Daniel Umansky +6 more
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Molecular Pain, 2021 Microglia activation following peripheral nerve injury has been shown to contribute to central sensitization of the spinal cord for the development of neuropathic pain.
Hyoung Woo Kim +2 more
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Targeting anti-inflammatory treatment can ameliorate injury-induced neuropathic pain. [PDF]
PLoS ONE, 2013 Tumor necrosis factor-α plays important roles in immune system development, immune response regulation, and T-cell-mediated tissue injury. The present study assessed the net value of anti-tumor necrosis factor-α treatment in terms of functional recovery ...
Katsuyuki Iwatsuki +7 more
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The Journal of Bone and Joint Surgery. British volume, 1988 Crushing of the radial side of the hand results in a wide spectrum of injuries varying from contusion of muscles to total loss. The main problem concerns the function of the thumb. The results of such injuries in 161 hands were reviewed. Those with mild injuries treated conservatively or by debridement alone had good results.
Luk, KDK +4 more
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Lipoprotein lipase is expressed in rat sciatic nerve and regulated in response to crush injury
Journal of Lipid Research, 2002 Male adult Sprague-Dawley rats were subjected to unilateral crush injury, and expression of LPL protein and mRNA were assessed as a function of time post-crush.
Patricia Uelmen Huey +3 more
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Trauma Case Reports, 2015 We describe a new technique of temporary stabilisation of a divergent Lisfranc fracture dislocation of foot with severe crush injury using an Ilizarov frame.
N. Ahmed, R. Kugan
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Trauma Case Reports, 2023 Crush injury is one of the most challenging decisions for a surgeon to decide whether to proceed with an amputation or salvage a limb.We presented a 24-year-old man who complained of having suffered a crushed thigh 12 h before admission to the hospital ...
Romy Deviandri +4 more
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