Status and global population trend of the Magellanic penguin Spheniscus magellanicus along the Argentine coast. [PDF]
Hombre JD +4 more
europepmc +1 more source
Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai +13 more
wiley +1 more source
Seroepidemiology of Chagas Disease Among Brazilian Indigenous Populations: Insights and Implications. [PDF]
de Siqueira IC +25 more
europepmc +1 more source
Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon +10 more
wiley +1 more source
Correction: Predicting median nerve depth from anthropometric features: A tool for safer invasive procedures. [PDF]
Mogedano-Cruz S +5 more
europepmc +1 more source
Passive Recovery of Vegetation after Herbivore Eradication on Santa Cruz Island, California
Roxanne S. Beltran +7 more
semanticscholar +1 more source
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou +10 more
wiley +1 more source
Identification of the emerging fungal pathogens in Brazilian children infected by <i>Giardia lamblia</i>. [PDF]
Motta CS +6 more
europepmc +1 more source
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang +13 more
wiley +1 more source
Caries and Socioeconomic Factors in Adults (19-60 Years Old): An Updated Systematic Review of Observational Studies. [PDF]
Cunha MAGM +4 more
europepmc +1 more source

