Results 61 to 70 of about 657,223 (265)
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Four specimens of primates were collected from the Santa Cruz Formation (Early–Middle Miocene) during expeditions undertaken by the Museo de la Plata, Museo Argentino de Ciencias Naturales “Bernardino Rivadavia”, and Duke University in 2013, 2014, and ...
Richard Frederick Kay +1 more
doaj
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Um inventário de fungos conidiais foi realizado em seis áreas de extrema importância biológica no bioma Caatinga. Foram coletadas 74 espécies, sendo sete novos registros para o Brasil. Heliocephala zimbabweensis Decock, V.
Alisson Cardoso Rodrigues da Cruz +1 more
doaj +1 more source
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
El ministerio expiatorio de Cristo la cruz (Parte III)
Por: Raoul ...
Raoul Dederen
doaj
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
The Santa Cruz Formation (Early–Middle Miocene) is one of the most widespread sedimentary units of the Argentine Patagonia. This unit contains an abundant and taxonomically diverse fossil vertebrate fauna, especially in mammals. Thus, the paleoecological
Leandro Martín Pérez +3 more
doaj
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
El ministerio expiatorio de Cristo la cruz (Parte II)
Por: Raoul ...
Raoul Dederen
doaj

