The Cadherin Cry1Ac Binding-Region is Necessary for the Cooperative Effect with ABCC2 Transporter Enhancing Insecticidal Activity of Bacillus thuringiensis Cry1Ac Toxin [PDF]
Toxins, 2019 Bacillus thuringiensis Cry1Ac toxin binds to midgut proteins, as cadherin (CAD) and ABCC2 transporter, to form pores leading to larval death. In cell lines, co-expression of CAD and ABCC2 enhance Cry1Ac toxicity significantly, but the mechanism remains ...
Yuemin Ma +9 more
doaj +3 more sources
Evaluation of GS-omega/kappa-Hxtx-Hv1a and Bt toxins against Bt-resistant and -susceptible strains of Helicoverpa zea (Boddie) and Spodoptera frugiperda (J.E. Smith). [PDF]
Pest Manag SciThe addition of 10 μg cm−2 of Cry1Ac to the surface of GS‐omega/kappa‐Hxtx‐Hv1a (ω/κ‐Hv1a) incorporated diet can significantly increase the mortality of Cry‐resistant Helicoverpa zea compared to diets without the Cry1Ac toxin. Abstract BACKGROUND Helicoverpa zea and Spodoptera frugiperda are destructive insect pests of cotton and corn.
Ross S +8 more
europepmc +2 more sources
Cry1 resistance in a CRISPR/Cas9-mediated HaCad1 gene knockout strain of the Australian cotton bollworm Helicoverpa armigera conferta (Lepidoptera: Noctuidae). [PDF]
Pest Manag SciKnocking out the HaCad1 gene in Helicoverpa armigera conferta decreases susceptibility to the Bacillus thuringiensis (Bt) toxins Cry1Ac and Cry1A.105. Abstract BACKGROUND Helicoverpa armigera is a highly polyphagous species that causes huge losses to agricultural and horticultural crops worldwide. In the cotton industry, H.
Fang CG +6 more
europepmc +2 more sources
Cry1Ac production is costly for native plants attacked by non‐Cry1Ac‐targeted herbivores in the field [PDF]
New Phytologist, 2018 Summary Plants are the primary producers in most terrestrial ecosystems and have complex defense systems to protect their produce. Defense‐deficient, high‐yielding agricultural monocultures attract abundant nonhuman consumers, but are alternatively defended through pesticide application and genetic engineering to produce insecticidal proteins such as
Erica McGale +3 more
openaire +3 more sources
Defoliation of Soybean Expressing Cry1Ac by Lepidopteran Pests [PDF]
Insects, 2018 Lepidoptera, stink bugs, and weevils are important pests in soybean. For lepidopteran control, insecticides and seed treatments are used. As an alternative, Bt soybean was developed to control primary pests of Lepidoptera such as Rachiplusia nu (Guenée) (Noctuidae), Chrysodeixisincludens (Walker) (Noctuidae), Anticarsia gemmatalis Hübner (Erebidae ...
María G. Murúa +4 more
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Mutations in a Novel Cadherin Gene Associated with Bt Resistance in Helicoverpa zea
G3: Genes, Genomes, Genetics, 2020 Transgenic corn and cotton produce crystalline (Cry) proteins derived from the soil bacterium Bacillus thuringiensis (Bt) that are toxic to lepidopteran larvae. Helicoverpa zea, a key pest of corn and cotton in the U.S., has evolved widespread resistance
Megan L. Fritz +4 more
doaj +1 more source
Toxins, 2021 Transgenic crops expressing Bacillus thuringiensis (Bt) insecticidal proteins have been extensively planted for insect pest control, but the evolution of Bt resistance in target pests threatens the sustainability of this approach.
Wenzhong Jin +4 more
doaj +1 more source
Toxins, 2022 Transgenic crops producing Bacillus thuringiensis (Bt) insecticidal proteins are grown widely for pest control, but the evolution of resistance in target pests could reduce their efficacy.
Shan Yu +5 more
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Decreased Cry1Ac activation by midgut proteases associated with Cry1Ac resistance in
Pest Management Science, 2018 AbstractBACKGROUNDField‐evolved resistance of Helicoverpa zea to Bacillus thuringiensis (Bt) toxin Cry1Ac was first reported more than a decade ago, yet the underlying mechanisms remain elusive. Towards understanding the mechanisms of resistance to Cry1Ac, we analyzed a susceptible (LAB‐S) and two resistant (GA and GA‐R) strains of H. zea.
Min Zhang +8 more
openaire +3 more sources
Journal of Integrative Agriculture, 2015 The Bacillus thuringiensis vegetative insecticidal protein, Vip3A, represents a new family of Bt toxin and is currently applied to commercial transgenic cotton.
Qian ZHANG +4 more
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