Results 51 to 60 of about 1,948 (159)

Lung Cryobiopsy for the Diagnosis of Interstitial Lung Diseases: A Series Contribution to a Debated Procedure

Medicina, 2019
Introduction: Transbronchial cryobiopsy is an alternative to surgical biopsy for the diagnosis of fibrosing interstitial lung diseases, although the role of this relatively new method is rather controversial.
Sergio Harari, Francesca Cereda, Federico Pane, Alberto Cavazza, Nikolaos Papanikolaou, Giuseppe Pelosi, Monica Scarioni, Elisabetta Uslenghi, Maurizio Zompatori, Antonella Caminati   +9 more
doaj   +1 more source

PD‐L1 Expression and Histopathological Features in EGFR‐Mutated Non‐Small Cell Lung Cancer: Implications for Immune Checkpoint Inhibitors After EGFR‐Tyrosine Kinase Inhibitors Resistance

Thoracic Cancer, Volume 17, Issue 3, February 2026.
This retrospective study elucidates the clinical significance of PD‐L1 expression in EGFR‐mutated non‐small cell lung cancer. High PD‐L1 expression (TPS ≥ 50%) was significantly associated with solid histological patterns and radiological solid nodules.
Toshiyuki Sumi, Taiki Ishigooka, Keigo Matsuura, Takumi Ikeda, Yuichi Yamada, Kotomi Arioka, Hirofumi Chiba   +6 more
wiley   +1 more source

GPNMB immunohistochemistry is a useful ancillary tool for the diagnosis of pulmonary lymphangioleiomyomatosis

Histopathology, Volume 88, Issue 3, Page 698-709, February 2026.
We evaluated the diagnostic utility of GPNMB immunohistochemistry in LAM. GPNMB showed strong expression in LAM cells, while the differential diagnostic mimics showed no or only low expression. Based on its 100% sensitivity and specificity in our cohort, GPNMB is a highly reliable immunohistochemical marker for the diagnosis of LAM.
Fatime Szalai, Judit Pápay, Katalin Dezső, Levente Kuthi, Anna Sebestyén, András Khoór, Ildikó Krencz   +6 more
wiley   +1 more source

Idiopathic pulmonary fibrosis: prognostic impact of histologic honeycombing in transbronchial lung cryobiopsy

Multidisciplinary Respiratory Medicine, 2019
Background Prognostic evaluation in idiopathic pulmonary fibrosis (IPF) may be important as it can guide management decisions, but the potential role of honeycomb changes in providing information about outcome and survival of patients with IPF ...
Claudia Ravaglia, Marcello Bosi, Athol U. Wells, Carlo Gurioli, Christian Gurioli, Alessandra Dubini, Sara Piciucchi, Silvia Puglisi, Susanna Mascetti, Antonella Arcadu, Sara Tomassetti, Venerino Poletti   +11 more
doaj   +1 more source

Comparison of cryobiopsy and forceps biopsy for the diagnosis of mediastinal lesions: A randomised clinical trial

Pulmonology
Introduction Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the standard approach for lung cancer staging. However, its diagnostic utility for other mediastinal diseases might be hampered by the limited tissue retrieved ...
T.-L. Cheng, Z.-S. Huang, J. Zhang, J. Wang, J. Zhao, K. Kontogianni, W.-L. Fu, N. Wu, W.M. Kuebler, F.J. Herth, Y. Fan   +10 more
doaj   +1 more source

Rare and Elusive: The Challenges of Bronchoscopically Diagnosing Pulmonary Mucosa‐Associated Lymphoid Tissue Lymphoma

Case Reports in Pulmonology, Volume 2026, Issue 1, 2026.
Primary pulmonary lymphomas (PPLs) are rare clinical entities representing 0.5%–1% of all pulmonary neoplasms, of which mucosa‐associated lymphoid tissue (MALT) lymphoma is the most common type (80%). PPLs are traditionally considered challenging to diagnose bronchoscopically given the rarity of these entities, small sample sizes, and the ancillary ...
Hamad Nasim, Robert Willim, Jason Beattie, Adnan Majid, Mihir Parikh, Kai Swenson, Nidhi Chaudhary   +6 more
wiley   +1 more source

Optimizing the endoscopic diagnosis of mediastinal lymphadenopathy: a glimpse on cryobiopsy

BMC Pulmonary Medicine, 2022
Etiological diagnosis of mediastinal lymphadenopathy represents a daily challenge. Endosonography (transesophageal and transbronchial ultrasound-guided needle aspiration) is the recommended technique in the first diagnostic work-up and in the mediastinal
Michele Mondoni, Giovanni Sotgiu
doaj   +1 more source

Delayed Massive Haemoptysis Following EBUS‐TBNA Revealing a Pseudoaneurysm of an Ectopic Bronchial Artery: A Rare Complication at the Crossroads of Interventional Pulmonology and Radiology

Respirology Case Reports, Volume 13, Issue 12, December 2025.
A 31‐year‐old woman with Budd–Chiari syndrome developed delayed massive haemoptysis 1 week after EBUS‐TBNA due to pseudoaneurysms arising from 4R lymph nodes. Diagnosis was confirmed by CT angiography and bronchoscopy, and successful microcoil embolisation achieved complete resolution.
Julien G. Cohen, Matthieu Papillard, Romain Messe   +2 more
wiley   +1 more source

Cryobiopsy in the diagnosis of bronchiolitis: a retrospective analysis of twenty-three consecutive patients

Scientific Reports, 2020
Bronchiolitis manifests as a variety of histological features that explain the complex clinical profiles and imaging aspects. In the period between January 2011 and June 2015, patients with a cryobiopsy diagnosis of bronchiolitis were retrospectively ...
Syakirin Sirol Aflah Syazatul, Sara Piciucchi, Sara Tomassetti, Claudia Ravaglia, Alessandra Dubini, Venerino Poletti   +5 more
doaj   +1 more source

Transbronchial cryobiopsy for diagnosis of pleuroparenchymal fibroelastosis

Respiratory Medicine Case Reports, 2020
Pleuroparenchymal fibroelastosis (PPFE) is a rare subtype of idiopathic interstitial pneumonias. PPFE mostly affects the upper lung zones and is characterized radiologically by pleural and subpleural fibrotic thickening with a reticular pattern. There is no established treatment for PPFE but lung transplantation can be considered for advanced stage ...
Hakami, Abdulrahman, Zwartkruis, Evita, Radonic, Teodora, Nossent, Esther J., Chua, Felix, Shah, Pallav L., Daniels, Johannes M. A.   +6 more
openaire   +5 more sources