Results 131 to 140 of about 26,860 (289)

Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids

open access: yesAdvanced Science, EarlyView.
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan   +19 more
wiley   +1 more source

Achieving exceptional Strength-Ductility at 4.2 K in High-Manganese Steels: The influence of pre-strain and aging on Manipulating microstructure and deformation behavior

open access: yesMaterials & Design
Pre-strain and aging (PA) treatment is essential in manufacturing Nb3Sn magnets and must be performed together with the outer jacket material. This imposes strict requirements on the aging resistance and cryogenic performance of the jacket material ...
Jia-kuan Ren   +8 more
doaj   +1 more source

Effect of Deep Cryogenic Treatment on Corrosion Behavior of AISI H13 Die Steel. [PDF]

open access: yesMaterials (Basel), 2021
Shinde T   +4 more
europepmc   +1 more source

Effect of deep cryogenic treatment on microstructure and mechanical properties of 18Ni (200) cryogenic maraging steel

open access: yes
The study investigated the effects of different cryogenic treatment time at −196 °C on the mechanical properties, microstructure, and fracture behavior of 18Ni (200) maraging steel.
Yujian Zhang   +4 more
core   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon   +21 more
wiley   +1 more source

Deep Cryogenic Treatment Characteristics of a Deformation-Processed Cu-Ni-Co-Si Alloy. [PDF]

open access: yesMaterials (Basel), 2022
Liu K   +7 more
europepmc   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

open access: yesAdvanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng   +8 more
wiley   +1 more source

Influence of the Deep Cryogenic Treatment on AISI 52100 and AISI D3 Steel's Corrosion Resistance. [PDF]

open access: yesMaterials (Basel), 2021
Jovičević-Klug P   +4 more
europepmc   +1 more source

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon   +20 more
wiley   +1 more source

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