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Pulmonary Cryptococcosis

Journal of Fungi, 2022
Pulmonary cryptococcosis describes an invasive lung mycosis caused by Cryptococcus neoformans or Cryptococcus gattii complex. It is often a high-consequence disease in both immunocompromised and immunocompetent populations, and may be misdiagnosed as pulmonary malignancy, leading to a delay in therapy.
Annaleise R. Howard-Jones, Rebecca Sparks, David Pham, Catriona Halliday, Justin Beardsley, Sharon C.-A. Chen   +5 more
openaire   +4 more sources

Seronegative Disseminated Cryptococcosis: A Case Report. [PDF]

Case Rep Med
Cryptococcal infection is a major cause of morbidity and mortality in immunocompromised patients, especially those with HIV/AIDS. The cryptococcal antigen (CrAg) lateral flow assay (LFA) has become an essential diagnostic tool due to its high sensitivity, specificity, and ability to produce rapid results.
Roell M, Baker K.
europepmc   +2 more sources

Rapidly Progressive Pulmonary Alveolar Proteinosis Following Cryptococcal Infection: Case Report and Literature Review. [PDF]

Respirol Case Rep
Here, we present a rare case of rapidly progressive pulmonary alveolar proteinosis caused by GM‐CSF antibodies following cryptococcal CNS and pulmonary infection. Due to the rapidity, bilateral whole lung lavage on VV‐ECMO was required to achieve remission.
Brookes SC, Sadler A, Troelnikov A, Hissaria P, Brown MV, Nguyen P, Kim J, Sarkar P.   +7 more
europepmc   +2 more sources

Epidemiology of Cryptococcosis and Cryptococcal Meningitis in a large retrospective cohort of patients after solid organ transplantation [PDF]

Open Forum Infectious Diseases, 2017
Background Cryptococcosis is the third most common invasive fungal infection in solid organ transplant (SOT) recipients. There are no nationally representative data describing the incidence, risk factors, and outcomes of cryptococcosis ...
George, Ige A, Olsen, Margaret A, Powderly, William G, Santos, Carlos A   +3 more
core   +3 more sources

Cryptococcosis [PDF]

Infectious Disease Clinics of North America, 2015
Cryptococcosis is an invasive mycosis caused by pathogenic encapsulated yeasts in the genus Cryptococcus. Cryptococcus gained prominence as a pathogen capable of widespread disease outbreaks in vulnerable populations. We have gained insight into the pathobiology of Cryptococcus, including the yeast' s capacity to adapt to environmental pressures ...
Maziarz, Eileen K., Perfect, John R.
openaire   +2 more sources

Automated Analysis of Cryptococcal Macrophage Parasitism Using GFP-Tagged Cryptococci [PDF]

, 2010
The human fungal pathogens Cryptococcus neoformans and C. gattii cause life-threatening infections of the central nervous system. One of the major characteristics of cryptococcal disease is the ability of the pathogen to parasitise upon phagocytic immune
A Casadevall, A Idnurm, AL Goldstein, B Bolanos, BJ Park, C Charlier, C Luberto, C Monari, CE Cross, DA Bobak, DL Goldman, DL Goldman, DL Oliveira, DL Toffaletti, E Brummer, EJ Byrnes 3rd, F Chretien, FM Griffin Jr, G Hu, GD Campbell, GS Bulmer, GS Bulmer, H Lee, H Ma, H Ma, H Ma, HF Nadrous, J Livet, Julian C. Rutherford, K Voelz, Kerstin Voelz, Kirsten Nielsen, L MacDougall, LA Knodler, LH Okagaki, M Alvarez, M Alvarez, M Alvarez, M Alvarez, M Del Poeta, M Feldmesser, M Feldmesser, M Shi, MC Lorenz, MF Miller, NC Shaner, P Ralph, R Bajpai, R Santangelo, R Velagapudi, RD Diamond, Robin C. May, S Geunes-Boyer, SC Tucker, SE Kidd, Simon A. Johnston, SM Levitz, TA Missall, TB Kechichian, TG Mitchell, TG Mitchell, TR Kozel, TW Christianson, X Dong, X Shao   +64 more
core   +13 more sources

Cryptococcosis

Seminars in Respiratory and Critical Care Medicine, 2020
AbstractCryptococcosis has become an important infection in both immunocompromised and immunocompetent hosts. Although Cryptococcus is mainly recognized by its ability to cause meningoencephalitis, it can infect almost any organ of the human body, with pulmonary infection being the second most common disease manifestation.
Sofia, Zavala, John W, Baddley
openaire   +3 more sources

Cryptococcal meningitis in HIV-infected patients: a longitudinal study in Cambodia. [PDF]

, 2010
To describe the frequency of diagnosis of cryptococcosis among HIV-infected patients in Phnom Penh, Cambodia, at programme entry, to investigate associated risk factors, and to determine the incidence of cryptococcal ...
Amornkul, Antinori, Chariyalertsak, Chhin, Darras-Joly, Dromer, French, Havlir, Heyderman, Jarvis, Jongwutiwes, Kong, Lortholary, Louie, Madec, Manosuthi, Micol, Mirza, Moosa, Pichith, Powderly, Senya, Singh, Sorvillo, Sungkanuparph   +24 more
core   +2 more sources

Limited Activity Of Miltefosine In Murine Models Of Cryptococcal Meningoencephalitis And Disseminated Cryptococcosis [PDF]

, 2013
Miltefosine is an alkyl phosphocholine with good oral bioavailability and in vitro activity against Cryptococcus species that has gained interest as an additional agent for cryptococcal infections.
Bocanegra, Rosie, Kirkpatrick, William R., Najvar, Laura K., Patterson, Thomas F., Sorrell, Tania C., Wiederhold, Nathan P.   +5 more
core   +1 more source

Cryptococcus, Pathological observations of five autopsy cases and one biopsy case [PDF]

, 1959
Pathologic, anatomical, and histological findings of 5 autopsy cases and one biopsy case of cryptococcosis have been described. Macroscopically the foci of the lung are grayish white or yellowish white in color and range in size from the small acinous ...
Inohara, Tsuyoshi, Kanamoto, Akihisa, Kuroda, Kiyoshi, Murase, Joji, Ogawa, Katsuo, Uejima, Akira   +5 more
core   +1 more source