Results 101 to 110 of about 34,978 (296)

Potential missed opportunities for diagnosis of cryptococcosis and the association with mortality: A cohort study

open access: yesEClinicalMedicine, 2020
Background: Cryptococcosis is one of the most common life-threatening opportunistic mycoses worldwide. Insidious presentation and slow onset of symptoms make it difficult to recognize, complicating the diagnostic process.
Ana S. Salazar   +7 more
doaj  

Enhancing Flucytosine Anticandidal Activity Using PEGylated Squalene Nanocarrier

open access: yesChemMedChem, Volume 20, Issue 1, January 2, 2025.
Our study focused on improving the effectiveness of the antifungal drug 5‐fluorocytosine (5FC) by loading it in micellar structures formed by PEGylated squalene copolymer. The obtained results for 5FC‐loaded micelles showed in vitro prolonged release under physiological conditions and improved in vitro antifungal activity without cytotoxicity for ...
Bogdan‐Florin Craciun   +3 more
wiley   +1 more source

Csf in 85 patients with aids and cns cryptococcosis

open access: yesArquivos de Neuro-Psiquiatria, 1992
In an eight years time period (July 1984-June 1992) CSF samples of 40718 patients were studied, and 610 were from patients with AIDS clinically diagnosed and immunologically confirmed through HIV antibodies detection.
J. A. Livramento   +5 more
doaj   +1 more source

The Significance of Mono‐ and Dual‐Effective Agents in the Development of New Antifungal Strategies

open access: yesChemical Biology &Drug Design, Volume 105, Issue 1, January 2025.
The future of treating challenging fungal infections lies in novel therapies targeting new antifungal targets, overcoming resistance mechanisms, and exploring innovative dual inhibitors. ABSTRACT Invasive fungal infections (IFIs) pose significant challenges in clinical settings, particularly due to their high morbidity and mortality rates.
Cengiz Zobi, Oztekin Algul
wiley   +1 more source

Significance of Combining Bronchoalveolar Lavage Fluid With Targeted Next‐Generation Sequencing in the Pathogen Detection‐Based Diagnosis of Pulmonary Infections

open access: yesThe Clinical Respiratory Journal, Volume 19, Issue 1, January 2025.
This study demonstrates the superior diagnostic efficacy of bronchoalveolar lavage fluid (BALF) combined with targeted next‐generation sequencing (tNGS) in identifying pathogens associated with lung infections compared to conventional microbiological tests (CMTs). The results suggest that tNGS is a valuable tool for accurate and comprehensive diagnosis,
Jiangbo Liu   +5 more
wiley   +1 more source

Disseminated cryptococcosis in a renal transplant recipient

open access: yesRespirology Case Reports, 2022
Key message Skin cryptococcosis often manifests as an umbilicated papule, and chest computed tomography findings of multiple nodules and cavities are also characteristic.
Seira Ozawa   +10 more
doaj   +1 more source

Cryptococcosis in Colombia: Compilation and Analysis of Data from Laboratory-Based Surveillance

open access: yesJournal of Fungi, 2018
The passive and voluntary surveillance of cryptococcosis in Colombia since 1997 has seen an increasing participating rate, revealing its importance to both in immunosuppressed and immunocompetent people.
Patricia Escandón   +3 more
semanticscholar   +1 more source

Virchow-Robin spaces : an anatomic variant or a pathologic sign? [PDF]

open access: yes, 2009
Virchow-Robin spaces surround blood vessels. Their walls are formed by prolongations of the pia mater and they have no communication with the subarachnoid space. VRS are often seen as well-delineated foci of cerebrospinal fluid signal on MR images.

core  

Retrospective evaluation of computed tomographic‐guided Tru‐Cut biopsies in 16 dogs and 14 cats with nasal cavity mass lesions

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 1, January/February 2025.
Abstract Background Approximately 80% of nasal masses in dogs and 91% of nasal masses in cats are reported to be malignant, but the currently reported diagnostic rate of neoplasia is 54% using blind or rhinoscopic biopsy techniques. Hypothesis/Objectives Describe the technique of computed tomography (CT)‐guided Tru‐Cut (Tru‐Cut biopsy needle, Merit ...
Jessica Milne   +3 more
wiley   +1 more source

Evans Medicine [PDF]

open access: yes, 1989
Newsletter of the Evans Memorial Department of Clinical Research and Preventive Medicine at University ...
Levinsky, Norman G.   +1 more
core  

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