Paradoxical emboli from calf and pelvic veins in cryptogenic stroke. [PDF]
PURPOSE: The increased prevalence of patent foramen ovale in patients with cryptogenic strokes suggests the occurrence of paradoxical embolism. The identification of deep venous thromboses (DVTs) in this population would strengthen this hypothesis.
Burgin, W Scott +6 more
core +1 more source
Transcranial doppler ultrasonography should it be the first choice for persistent foramen ovale screening? [PDF]
BACKGROUND: Persistent foramen ovale (PFO) is considered a cause of cryptogenic stroke and a risk factor for neurological events in young patients. The reference standard for identifying a PFO is contrast-enhanced transesophageal echocardiography (TEE ...
Anna Kabłak-Ziembicka +9 more
core +1 more source
A perspective: PLA2G4A as drug target for vascular inflammation in Alzheimer's disease
Abstract Anti‐amyloid therapies for Alzheimer's disease (AD) modestly slow cognitive decline but carry significant risk of amyloid‐related imaging abnormalities (ARIAs), brain swelling, and hemorrhage, particularly in apolipoprotein E ε4 carriers. Cerebral amyloid angiopathy (CAA) and vascular inflammation drive this vulnerability, highlighting the ...
Ambreen Kanwal +12 more
wiley +1 more source
ABSTRACT The presence of the bilateral claustrum sign in new‐onset refractory status epilepticus (NORSE) should prompt consideration of Hashimoto's encephalopathy, even without thyroid dysfunction. Early recognition and corticosteroid therapy can be lifesaving, emphasizing an autoimmune‐inflammatory mechanism underlying this rare presentation.
Zahra‐Sadat Mirian +4 more
wiley +1 more source
Abstract Objective This study aimed to identify risk factors and develop a predictive scoring system for autoimmune‐associated epilepsy in subjects with autoimmune encephalitis presenting with new onset refractory status epilepticus (NORSE). Methods This retrospective, multicenter, cohort study included subjects who presented with NORSE at the onset of
Simona Lattanzi +50 more
wiley +1 more source
Evaluation of a clinical tool for early etiology identification in status epilepticus. [PDF]
OBJECTIVES: Because early etiologic identification is critical to select appropriate specific status epilepticus (SE) management, we aim to validate a clinical tool we developed that uses history and readily available investigations to guide prompt ...
Alvarez, V. +6 more
core +1 more source
Cerebral Infarction: Epidemiology, Classification, Mechanisms, Diagnosis, and Management
Within minutes after ischemia onset, deprivation of oxygen and glucose leads to rapid ATP depletion, resulting in failure of Na+/K+‐ATPase activity and membrane depolarization. This ionic imbalance promotes uncontrolled synaptic release of glutamate and excessive activation of postsynaptic NMDA and AMPA receptors.
Meibiao Zhang +4 more
wiley +1 more source
HEart and BRain interfaces in Acute ischemic Stroke (HEBRAS) – rationale and design of a prospective oberservational cohort study [PDF]
Background An effective diagnostic work-up in hospitalized patients with acute ischemic stroke is vital to optimize secondary stroke prevention. The HEart and BRain interfaces in Acute ischemic Stroke (HEBRAS) study aims to assess whether an enhanced MRI
Endres, Matthias +5 more
core +2 more sources
Patent Foramen Ovale Closure Procedure
Patent foramen ovale is strongly associated with cryptogenic stroke. Various clinical trials has shown the association between cryptogenic stroke and incidence of undelrying patent foramen ovale, these trials also shown the decrease of cryptogenic stroke
Arwin Saleh Mangkuanom, Doni Firman
doaj
Embolic stroke of unknown source (ESUS) in patients with atrial septum defect and patent foramen ovale: difference and similarities [PDF]
Introduction Paradoxical embolism from right-to-left shunt through a patent foramen ovale (PFO) is a well-characterized cause of embolic strokes of undetermined source (ESUS).
DELABAYS, C.
core

