Results 51 to 60 of about 16,068 (216)

Diagnostic Yield of TEE in Patients with Cryptogenic Stroke and TIA with Normal TTE: A Systematic Review and Meta-Analysis

Neurology International, 2021
Introduction: The role of transesophageal echocardiography (TEE) in cryptogenic stroke and transient ischemic attack (TIA) with normal transthoracic echocardiography (TTE) remains controversial in the absence of definite guidelines. We aimed to perform a
Shamik Shah, Preeti Malik, Urvish Patel, Yunxia Wang, Gary S. Gronseth   +4 more
doaj   +1 more source

Cryptogenic stroke, embolic stroke of unknown source, and the left atrial septal pouch: the role of transesophageal echocardiography

Journal of Stroke and Cerebrovascular Diseases
Background: Cryptogenic stroke accounts for a substantial proportion of ischemic strokes and often poses a diagnostic challenge due to the limitations of the TOAST classification in identifying atypical mechanisms.
Jennifer Xu, MD, Jihoon Kang, MD, Jonathan Schilling, MD MBA, Annlia Paganini-Hill, PhD, Marissa Ericson, PhD, Jin Kyung Kim, MD PhD, Mark Fisher, MD   +6 more
doaj   +1 more source

Predictors of Survival in Patients With Ischemic Stroke and Active Cancer: A Prospective, Multicenter, Observational Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Limited data exist on the prognostic factors for patients with ischemic stroke and active cancer. Methods and Results We conducted a prospective, multicenter, observational study in Japan, including patients with acute ischemic stroke and ...
Yasufumi Gon, Manabu Sakaguchi, Hiroshi Yamagami, Soichiro Abe, Hiroyuki Hashimoto, Nobuyuki Ohara, Daisuke Takahashi, Yuko Abe, Tsutomu Takahashi, Takaya Kitano, Shuhei Okazaki, Kenichi Todo, Tsutomu Sasaki, Satoshi Hattori, Hideki Mochizuki   +14 more
doaj   +1 more source

CT angiography of the aorta is superior to transesophageal echocardiography for determining stroke subtypes in patients with cryptogenic ischemic stroke [PDF]

, 2012
Background: The etiology of ischemic strokes remains cryptogenic in about one third of patients, even after extensive workup in specialized centers. Atherosclerotic plaques in the aorta can cause thromboembolic events but are often overlooked.
Artemis, Dimitrios, Chatzikonstantinou, Anastasios, Fink, Christian, Flüchter, Stephan, Hennerici, Michael G., Krissak, Radko, Schäfer, A., Schönberg, Stefan O.   +7 more
core   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

What general practitioners need to know about patent foramen ovale [PDF]

, 2014
A patent foramen ovale (PFO) consists of a hole between the right and left atriums of the heart that did not close the way it should after birth. Twenty five percent of the population have a PFO, but this usually does not cause problems, because the ...
Saliba, Mario
core  

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

Prevalence of CADASIL and Fabry Disease in a Cohort of MRI Defined Younger Onset Lacunar Stroke. [PDF]

, 2015
BACKGROUND AND PURPOSE: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), caused by mutations in the NOTCH3 gene, is the most common monogenic disorder causing lacunar stroke and cerebral small vessel ...
Baker, Rob, Bevan, Steve, Hassan, Ahamad, Hughes, Derralynn A, Kilarski, Laura L, Markus, Hugh S, Rutten-Jacobs, Loes CA, UK Young Lacunar Stroke DNA Study   +7 more
core   +11 more sources

Diagnosis, prognosis, and management of cryptogenic stroke [version 1; referees: 3 approved]

F1000Research, 2016
Despite many advances in our understanding of ischemic stroke, cryptogenic strokes (those that do not have a determined etiology) remain a diagnostic and therapeutic challenge.
Cen Zhang, Scott Kasner
doaj   +1 more source

ECG Smart Monitoring versus Implantable Loop Recorders for Atrial Fibrillation Detection after Cryptogenic Stroke—An Overview for Decision Making

Journal of Cardiovascular Development and Disease, 2023
Up to 20% of patients with ischemic stroke or transient ischemic attack have a prior history of known atrial fibrillation (AF). Additionally, unknown AF can be detected by different monitoring strategies in up to 23% of patients with cryptogenic or non ...
Thomas Pezawas
doaj   +1 more source