Octaarginine Improves the Efficacy of Nitazoxanide against Cryptosporidium parvum
Cryptosporidiosis is an intestinal disease that affects a variety of hosts including animals and humans. Since no vaccines exist against the disease till date, drug treatment is the mainstay of disease control. Nitazoxanide (NTZ) is the only FDA-approved
Tran Nguyen-Ho-Bao +6 more
doaj +1 more source
Cryptosporidium parvum: an emerging occupational zoonosis in Finland
Background Cryptosporidiosis has increased in recent years in Finland. We aimed to identify risk factors for human cryptosporidiosis and to determine the significance of Cryptosporidium parvum as a causative agent.
Tuulia Enbom +5 more
doaj +1 more source
Modeling cryptosporidiosis in humans and cattle: Deterministic and stochastic approaches
Cryptosporidiosis is a zoonotic disease caused by Cryptosporidium. The disease poses a public and veterinary health problem worldwide. A deterministic model and its corresponding continuous time Markov chain (CTMC) stochastic model are developed and ...
Faraja Luhanda +2 more
doaj +1 more source
Cryptosporidium Priming Is More Effective than Vaccine for Protection against Cryptosporidiosis in a Murine Protein Malnutrition Model [PDF]
Cryptosporidium is a major cause of severe diarrhea, especially in malnourished children. Using a murine model of C. parvum oocyst challenge that recapitulates clinical features of severe cryptosporidiosis during malnutrition, we interrogated the effect ...
A Blikslager +105 more
core +5 more sources
Foodborne cryptosporidiosis [PDF]
Foodborne illness, the majority of which is caused by enteric infectious agents, costs global economies billions of dollars each year. The protozoan parasite Cryptosporidium is particularly suited to foodborne transmission and is responsible for >8 million cases of foodborne illness annually.
Ryan, U., Hijjawi, N., Xiao, L.
openaire +2 more sources
Cryptosporidium, Enterocytozoon, and Cyclospora Infections in Pediatric and Adult Patients with Diarrhea in Tanzania. [PDF]
Cryptosporidiosis, microsporidiosis, and cyclosporiasis were studied in four groups of Tanzanian inpatients: adults with AIDS-associated diarrhea, children with chronic diarrhea (of whom 23 of 59 were positive [+] for human immunodeficiency virus [HIV]),
Abel E. Msengi +16 more
core +1 more source
Disseminated Cryptosporidium infection in an infant with CD40L deficiency
The protozoan Cryptosporidium affects the digestive tract of humans and animals. Cryptosporidiosis leads to diarrhoea mimicking a cholera-like course with dehydration and may even result in death in immunodeficient patients, as patients with hyper-IgM ...
Fleur Dupuy +4 more
doaj +1 more source
Zoonotic cryptosporidiosis [PDF]
The widespread usages of molecular epidemiological tools have improved the understanding of cryptosporidiosis transmission. Much attention on zoonotic cryptosporidiosis is centered on Cryptosporidium parvum. Results of genotype surveys indicate that calves are the only major reservoir for C. parvum infections in humans. The widespread presence of human-
Lihua, Xiao, Yaoyu, Feng
openaire +2 more sources
Cryptosporidiosis Modulates the Gut Microbiome and Metabolism in a Murine Infection Model
Cryptosporidiosis is a major human health concern globally. Despite well-established methods, misdiagnosis remains common. Our understanding of the cryptosporidiosis biochemical mechanism remains limited, compounding the difficulty of clinical diagnosis.
Avinash V. Karpe +13 more
doaj +1 more source
Cryptosporidiosis and Filtration of Water from Loch Lomond, Scotland
Previous evidence has suggested an association between consumption of unfiltered water from Loch Lomond, Scotland, and cryptosporidiosis. Before November 1999, this water had been only microstrained and disinfected with chlorine; however, since that time,
Kevin G.J. Pollock +3 more
doaj +1 more source

