Results 91 to 100 of about 589,086 (216)

Targeting Glutamine Metabolism Transporter SLC25A22 Enhances CD8+ T‐Cell Function and Anti‐PD‐1 Therapy Efficacy in Cervical Squamous Cell Carcinoma: Integrated Metabolomics, Transcriptomics and T‐Cell‐Incorporated Tumor Organoid Studies

Advanced Science, EarlyView.
Through metabolomic and transcriptomic analyses, a glutamine‐enriched, immunosuppressive microenvironment is identified in cervical squamous cell carcinoma (CSCC), highlighting the glutamine transporter SLC25A22 as a key regulator of glutamine metabolism, immune checkpoint activation, and CD8+ T‐cell cytotoxicity.
Tingting Ren, Junjun Qiu, Fanghua Chen, Qian Jiang, Qinqin Liu, Tong Wu, Hua Jiang, Keqin Hua   +7 more
wiley   +1 more source

Superelastic and Ultra‐Soft MXene/CNF Aerogel@PDMS‐Based Dual‐Modal Pressure Sensor for Complex Stimuli Monitoring

Advanced Science, EarlyView.
A triboelectric‐piezoresistive dual‐modal pressure sensor based on superelastic and ultrasoft MXene/cellulose nanofiber (CNF) aerogel@PDMS is fabricated. The sensor exhibits high sensitivity and stable sensing performance via a dual mechanism. Through the effective combination of these two mechanisms, comprehensive monitoring of complex stimuli can be ...
Ao Wang, Zhenqiu Gao, Shaokuan Wu, Yihan Wei, Bohan Lu, Jia Shi, Lanyue Shen, Yina Liu, Xuhui Sun, Zhen Wen   +9 more
wiley   +1 more source

Bioinspired Liquid‐Free Ion‐Conductive Elastomers with Ultrahigh Mechanical Strength and Excellent Ionic Conductivity for Multifunctional Flexible Sensing Applications

Advanced Science, EarlyView.
⁻Inspired by the “brick wall” structure of pearl layer, FLICE‐110% liquid‐free ionic conductive elastomer had high mechanical strength (5.46 MPa), excellent ionic conductivity (3.29 × 10−4 S cm−1) and resilience. It can be used in smart music boxes, airplane wings and control manipulators.
Zequan Li, Jingjing Tang, Xuwei Wang, Fuqi Wang, Fangyan Ou, Wenyu Pan, Changsheng Wang, Ting Xie, Chuang Ning, Xiwei Xu, Jiamin Liu, Qihua Liang, Wei Gao, Shuangliang Zhao   +13 more
wiley   +1 more source

PlantGPT: An Arabidopsis‐Based Intelligent Agent that Answers Questions about Plant Functional Genomics

Advanced Science, EarlyView.
PlantGPT integrates 60 000+ plant research articles with Arabidopsis phenotype‐gene data through retrieval‐augmented generation and fine‐tuning of Llama3‐8B. This open‐source, specialized AI system outperforms general large language models in plant gene‐phenotype relationships, establishing a new paradigm for functional genomics research and molecular ...
Ruixiang Zhang, Yu Wang, Weiyang Yang, Jun Wen, Weizhi Liu, Shipeng Zhi, Guangzhou Li, Nan Chai, Jiaqi Huang, Yongyao Xie, Xianrong Xie, Letian Chen, Miao Gu, Yao‐Guang Liu, Qinlong Zhu   +14 more
wiley   +1 more source

Directional Ion Transport Through Nanoarchitected 1D Mesochannels: 2D Polymer Interfacial Engineering for High‐Efficiency Capacitive Deionization

Advanced Science, EarlyView.
The engineering 2D polymer/graphene heterostructures with aligned 1D mesochannels synergizes directional ion transport pathways, corrosion‐resistant interfaces, and rapid electron highways, overcoming traditional bottlenecks. The design scalability and tunability enable universal adaptation to diverse redox‐active polymers, while its mechanistic ...
Chen Tang, Hongli Chen, Qian Li, Changle Li, Ying Li, Azhar Alowasheeir, Zeinhom M El‐Bahy, Guoxiu Wang, Chongyin Zhang, Yusuke Yamauchi, Xingtao Xu   +10 more
wiley   +1 more source

A Generative AI‐Assisted Piezo‐MEMS Ultrasound Device for Plant Dehydration Monitoring

Advanced Science, EarlyView.
This study introduces a complementary metal–oxide–semiconductor (CMOS)‐compatible wearable piezoelectric micromachined ultrasound transducers (PMUTs) that sandwiches the leaf (PMUT–Leaf–PMUT, PLP) and employs generative artificial intelligence for real‐time analysis.
Kaustav Roy, Darren Sim, Luwei Wang, Zixuan Zhang, Xinge Guo, Yao Zhu, Sanjay Swarup, Chengkuo Lee   +7 more
wiley   +1 more source

Untying Surface Chemistry and Emulsion Stability to Construct Multifunctional Pickering Emulsion SERS Sensors for Pretreatment‐Free Quantitative Analysis in Bio‐Media

Advanced Science, EarlyView.
A dual‐particle interfacial self‐assembly approach is used to create surface‐accessible Pickering emulsions with Au@Prussian blue nanoparticles acting as the functional component. These emulsions have strong plasmonic properties and are equipped with molecular sieves and internal standards.
Yingrui Zhang, Chunchun Li, Ruairi Carland, Ziwei Ye, Steven E. J. Bell, Yikai Xu   +5 more
wiley   +1 more source

Low‐Temperature Annealing Triggered Abnormal Strengthening in a Complex Concentration Alloy via Evolutive Short‐Range Ordering

Advanced Science, EarlyView.
Low‐temperature annealing enhances strength, ductility, and work hardening in CoNiV MEA. This originates from multi‐scale chemical short‐range orderings (SROs) formed during annealing, which promote dislocation slip planarity and reduce entanglement, enabling balanced mechanical properties through ordering strengthening.
Yihan Wang, Yuan Wu, Yong Yu, Yang He, Xinyang Yu, Xiongjun Liu, Hui Wang, Suihe Jiang, Xiaobin Zhang, Zhaoping Lu   +9 more
wiley   +1 more source

Prospect of Cascade Catalysis in Magnesium‐Sulfur Batteries from Desolvation to Conversion Reactions

Advanced Science, EarlyView.
The dissolution and conversion reactions at the cathode interface of Mg‐S batteries are systematically summarized. This review focuses on the problems and solutions of diffusion/desolvation Mg2+ migration barrier at the sulfur/electrolyte interface as well as the current development and design of S cathodes in Mg‐S batteries under catalysis ...
Qinghua Guan, Jing Zhang, Yongzheng Zhang, Xiaomin Cheng, Jing Dong, Lujie Jia, Hongzhen Lin, Jian Wang   +7 more
wiley   +1 more source

High‐Performance Conductive Elastomers Based on Deep Eutectic Solvents and Polyvinyl Alcohol for Flexible Monitoring Sensors

Advanced Electronic Materials, EarlyView.
A novel conductive elastomer is developed by incorporating deep eutectic solvents into a PVA/Polyacrylic Acid (PAA) network. The synergistic effects of dynamic hydrogen bonds, ionic interactions, and chemical crosslinking result in a highly flexible and dense polymer structure, while the integration of sodium chloride ensures excellent conductivity and
Pinwen Wang, Shouhua Han, Zhipeng Hou, Sihang Ren, Muxin Zhao, Liqun Yang   +5 more
wiley   +1 more source