Results 81 to 90 of about 34,265 (250)

Pharmacokinetics of Intramuscular and Intravenous Glycopyrrolate in Juvenile New Zealand White Rabbits

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Glycopyrrolate is an alternative to atropine to treat bradyarrhythmias in anesthetized rabbits; however, there are no pharmacokinetic studies in the literature. Six female New Zealand White rabbits received glycopyrrolate 0.05 mg/kg intravenously (IV) in the cephalic vein or intramuscularly (IM) in a complete crossover design.
Jocelyn Marchiori   +8 more
wiley   +1 more source

Shock

open access: yesJournal of Health Science and Medical Research (JHSMR), 2003
Shock is a syndrome of poor tissue perfusion that causes imbalance of oxygen demand and oxygen supply. Delayed diagnosis and treatment of shock may increase morbidity and mortality of the patients.
R Bhurayanontachai
doaj  

Valproic acid for treatment of traumatic brain injury: Study protocol for the VIBRANT prospective randomized trial

open access: yesTransfusion, EarlyView.
Abstract Background Traumatic brain injury (TBI) carries significant mortality and morbidity in civilian and military populations. Current treatment guidelines for TBI are primarily supportive, and no pharmacological agent exists to attenuate the progression of brain injury.
Maxime A. Visa   +9 more
wiley   +1 more source

Endothelial thrombomodulin—Its role in trauma‐induced coagulopathy

open access: yesTransfusion, EarlyView.
Abstract Background Trauma‐induced coagulopathy (TIC) describes a complex set of coagulation changes affecting severely injured patients. The thrombomodulin‐protein C axis is central to the evolution of TIC. Soluble thrombomodulin (sTM) levels are elevated after injury and predict poor clinical outcomes.
Jeries Abu‐Hanna   +7 more
wiley   +1 more source

Successful Resuscitation in a Model of Asphyxia and Hemorrhage to Test Different Volume Resuscitation Strategies. A Study in Newborn Piglets After Transition

open access: yesFrontiers in Pediatrics, 2018
Background: Evidence for recommendations on the use of volume expansion during cardiopulmonary resuscitation in newborn infants is limited.Objectives: To develop a newborn piglet model with asphyxia, hemorrhage, and cardiac arrest to test different ...
Marc R. Mendler   +9 more
doaj   +1 more source

The anion study: effect of different crystalloid solutions on acid base balance, physiology, and survival in a rodent model of acute isovolaemic haemodilution [PDF]

open access: yes, 2018
Background: Commercially available crystalloid solutions used for volume replacement do not exactly match the balance of electrolytes found in plasma. Large volume administration may lead to electrolyte imbalance and potential harm.
Dyson, A   +5 more
core   +2 more sources

Nationwide pediatric prehospital blood product use after motor vehicle crashes 2020–2023

open access: yesTransfusion, EarlyView.
Abstract Background Previous studies suggest that in children with hemorrhagic shock following injury, prehospital blood transfusion improves survival. Quantifying and understanding the current demand for blood transfusion will help us improve the use and availability of prehospital blood for pediatric patients.
Chandler A. Annesi   +10 more
wiley   +1 more source

Renal and visceral protection in thoracoabdominal aortic surgery [PDF]

open access: yes, 2014
ObjectivesOpen thoracoabdominal aortic aneurysm (TAAA) repair traditionally carries substantial perioperative morbidity and mortality, primarily from distal aortic ischemia.
Aftab, Muhammad, Coselli, Joseph S.
core   +1 more source

Prophylactic crystalloids or prophylactic crystalloids with ephedrine: Comparison of hemodynamic effects during caesarean section under spinal anaesthesia using 0.5% bupivacaine

open access: yesJournal of Obstetric Anaesthesia and Critical Care, 2017
Background: Spinal anaesthesia is usually chosen for caesarean section not only because of its faster onset and reliability but also because general anaesthesia is associated with more complications.
Bharath Kumar Hegde   +1 more
doaj   +1 more source

LCCL protein complex formation in Plasmodium is critically dependent on LAP1. [PDF]

open access: yes, 2017
Successful sporogony of Plasmodium berghei in vector mosquitoes requires expression of a family of six modular proteins named LCCL lectin domain adhesive-like proteins (LAPs).
Annie Z. Tremp   +25 more
core   +3 more sources

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