Results 61 to 70 of about 945 (160)

Pricing dynamics and herding behaviour of NFTs

European Financial Management, Volume 31, Issue 2, Page 670-710, March 2025.
Abstract This paper analyzes the sales of 875,389 art nonfungible tokens (NFTs) on the Ethereum blockchain to identify the key determinants influencing NFT pricing and market dynamics. We find that market liquidity and trade volume are strong predictors of NFT prices. Contrarily, social media activity negatively correlates with prices.
Gilbert Fridgen, Roman Kräussl, Orestis Papageorgiou, Alessandro Tugnetti   +3 more
wiley   +1 more source

Acrylamide induces spatiotemporal metabolic profiling disturbance via targeting taurine and hypotaurine metabolism during early zebrafish development

Food Frontiers, Volume 6, Issue 1, Page 282-299, January 2025.
This study provides in‐depth evidence on the metabolic regulation of zebrafish embryos with acrylamide exposure at different zebrafish developmental stages. The pattern of significantly changed metabolites revealed that acrylamide exposure has a detrimental effect on early heart development in zebrafish due to the inhibition of de novo synthesis of ...
Anli Wang, Jia Zeng, Xiaoran Song, Yingyu Huang, Jianxin Yao, Li Zhu, Yuchen Gao, Binjie Wang, Yuanzhao Wu, Zhongshi Xu, Ruonan Zheng, Yazhou Qin, Jiye Wang, Weixuan Yao, Xuzhi Wan, Haoyu Li, Pan Zhuang, Jingjing Jiao, Shulin Zhuang, Yu Zhang   +19 more
wiley   +1 more source

Research on the Antiaging Activity of Licorice Water Extract in Aging Mice via Antioxidation, Neuronal Protection, Gut Microbiota Restoration, and PI3K/AKT/mTOR Modulation

Mediators of Inflammation, Volume 2025, Issue 1, 2025.
Background Aging is a multifaceted physiological process characterized by progressive multiorgan dysfunction, oxidative stress, neuronal injury, cognitive impairment, and alterations in gut microbiota composition. Licorice, a widely used traditional medicinal herb, contains diverse bioactive constituents; however, its overall antiaging properties and ...
Yanhua Yu, Baiji Xue, Tong Liu, Xianwen Yue, Dawei Liu, Xia Yu, Yang Xu, Xueliang Zhao, Xuefeng Li, Palash Mandal   +9 more
wiley   +1 more source

Bile acid regulation of hepatic CSAD

, 2014
AimBile acid synthesis is regulated by nuclear receptors including farnesoid X receptor (FXR) and small heterodimer partner (SHP), and by fibroblast growth factor 15/19 (FGF15/19). We hypothesized that hepatic cysteine sulfinic acid decarboxylase (CSAD) (a key enzyme in taurine synthesis) is regulated by bile acids (BA).
Kerr, Thomas A, Matsumoto, Yuri, Matsumoto, Hitoshi, Xie, Yan, Hirschberger, Lawrence L, Stipanuk, Martha H, Anakk, Sayeepriyadarshini, Moore, David D, Watanabe, Mitsuhiro, Kennedy, Susan, Davidson, Nicholas O   +10 more
openaire   +2 more sources

Characterization of the PLP-dependent decarboxylases GADL1 and CSAD

, 2022
Pyridoxal 5’-phosphate (PLP) -dependent enzymes constitute an essential superfamily of enzymes for all living organisms. Due to the chemistry of their cofactor, PLP, these enzymes catalyze a wide variety of reactions. PLP-dependent decarboxylases (PLPDCs) play key roles in amino acid metabolism and are considered important biocatalysts for the ...
openaire   +1 more source

De novo biosynthesis and nicotinamide biotransformation of nicotinamide mononucleotide by engineered yeast cells

Microbial Biotechnology, Volume 17, Issue 11, November 2024.
Metabolic engineering of P. pastoris achieves NMN production by semi‐biosynthesis and de novo biosynthesis, which represents the highest yield of de novo synthesis of NMN from basic carbon sources yet reported. Abstract β‐Nicotinamide mononucleotide (NMN) is a precursor of NAD+ in mammals.
Yanna Ren, Bei Han, Shijie Wang, Xingbin Wang, Qi Liu, Menghao Cai   +5 more
wiley   +1 more source

Foreign exchange market herd behaviour: empirical study in ASEAN-5 countries [PDF]

AJAR (Asian Journal of Accounting Research)
Purpose – The study examines the herd behaviour in Association of Southeast Asian Nations (ASEAN)-5 foreign exchange markets: Indonesia, Malaysia, Philippines, Singapore and Thailand. Design/methodology/approach – We use the daily data as a sample. Cross-
Nevi Danila, Priyanka Aggarwal
doaj   +1 more source

Advancements in oral insulin: A century of research and the emergence of targeted nanoparticle strategies

European Journal of Lipid Science and Technology, Volume 126, Issue 7, July 2024.
Various nanoscale drug delivery systems have been developed to improve insulin absorption in the intestines through oral administration. Abstract With the growing prevalence of diabetes, there is an urgent demand for a user‐friendly treatment option that minimizes side effects related to the use of subcutaneous injections.
Yue Han, Julie Spicer, Yuan Huang, Craig Bunt, Mengyang Liu, Jingyuan Wen   +5 more
wiley   +1 more source

Herding behaviour in digital currency markets: An integrated survey and empirical estimation

Heliyon, 2020
This paper reviews the empirical literature on the highly popular phenomenon of herding behaviour in the markets of digital currencies. Furthermore, a comparison takes place with outcomes from earlier studies about traditional financial assets. Moreover,
Nikolaos A. Kyriazis
doaj   +1 more source

Surprisal-based algorithm for detecting anomalies in categorical data

Data Science and Management
Anomaly detection is an important research area in a diverse range of real-world applications. Although many algorithms have been proposed to address anomaly detection for numerical datasets, categorical and mixed datasets remain a significant challenge,
Ossama Cherkaoui, Houda Anoun, Abderrahim Maizate   +2 more
doaj   +1 more source