A Novel Method for Building Contour Extraction Based on CSAR Images
Circular synthetic aperture radar (CSAR) can obtain more complete scattering characteristics by observing the target with different azimuth angles. Therefore, extracting the complete structure of the target from CSAR images is of great significance for ...
Jia Zhao, Daoxiang An, Leping Chen
doaj +3 more sources
Studying CSAR systems using IRF-CSAR
In this paper, Impulse Response Function in Circular Synthetic Aperture Radar Imaging (IRF-CSAR), which is a special version of Impulse Response Function in Ultrawideband-Ultrawidebeam Synthetic Aperture Radar Imaging (IRF-USAR), is presented and shown to be valid for representing the CSAR image of a point-like scatterer. IRF-CSAR can therefore be used
V.T. Vu +3 more
openaire +2 more sources
CSAR: a contig scaffolding tool using algebraic rearrangements [PDF]
Abstract Summary Advances in next generation sequencing have generated massive amounts of short reads. However, assembling genome sequences from short reads still remains a challenging task. Due to errors in reads and large repeats in the genome, many of current assembly tools usually produce just ...
Kun-Tze Chen +6 more
openaire +4 more sources
Integration of Ligand and Structure Based Approaches for CSAR-2014 [PDF]
The prediction of binding poses and affinities is an area of active interest in computer-aided drug design (CADD). Given the documented limitations with either ligand or structure based approaches, we employed an integrated approach and developed a rapid protocol for binding mode and affinity predictions.
Philip Prathipati, Kenji Mizuguchi
openaire +5 more sources
CSAR: The Cross-Sectional Autoregression Model [PDF]
The forecasting of time series data is an integral component for management, planning, and decision making. Following the Big Data trend, large amounts of time series data are available in many application domains. The highly dynamic and often noisy character of these domains in combination with the logistic problems of collecting data from a large ...
Claudio Hartmann +3 more
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A Comprehensive <sup>19</sup>F NMR Framework for Fragment-Based Drug Discovery: The Validated Screening Library OpenFL600 and Efficient Affinity Ranking by CSAR. [PDF]
NMR screening is a powerful method for hit detection in drug‐discovery. We designed and validated the OpenFL600 19F$^{19}{\rm F}$ NMR library to probe diverse targets, including RNA, GPCRs, kinases, and proteases. This library yields target‐specific ligands without generating promiscuous binders.
Rüdisser SH +16 more
europepmc +2 more sources
Circular synthetic aperture radar (CSAR), as a novel imaging mode, enables multiaspect imaging of the same scene, capturing scattering information from different azimuth angles, thereby significantly enhancing the performance of SAR image interpretation.
Xiaodong Yan +3 more
doaj +2 more sources
CSAKD: Determining Absolute Ligand Affinities From <sup>19</sup>F NMR Chemical Shift Anisotropy. [PDF]
Affinity determination is crucial in drug discovery, yet remains difficult for weakly binding fragments. We introduce chemical shift anisotropy KD$K_{\text{D}}$ (CSAKD) by 19F$^{19}{\rm F}$ NMR relaxation experiments, a titration‐free method that requires no isotopic labeling.
Rüdisser SH, Stadler G, Gossert AD.
europepmc +2 more sources
Alkyltransferase Ribozyme for Site-Specific N<sup>4</sup>-Cytidine Alkylation. [PDF]
CSAR is the first ribozyme that catalyzes direct alkylation of an exocyclic amino group of an RNA nucleobase. The ribozyme was isolated as a self‐labeling catalyst from an in vitro selection library and engineered into a trans‐active ribozyme that catalyzes the transfer of a benzyl group from an O6‐modifed guanine to the N4 amino group of a specific ...
Dorinova E, Walunj MB, Höbartner C.
europepmc +2 more sources
Engineering and Tuning of High Quality Hexagonal Boron Nitride Nanophotonic Resonators. [PDF]
The manuscript explores nanofabrication protocols for photonic crystal cavities and microdisk resonators from hexagonal boron nitride. High Q cavities are fabricated and their resonances are controllably tuned. The work is important for future realization of quantum technologies with hexagonal boron nitride.
Schaeper OC +6 more
europepmc +2 more sources

