Results 31 to 40 of about 5,163 (240)

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using Hyperpolarized 13C MRI and PET

Advanced Science, EarlyView.
This work presents a clinically deployable simultaneous PET/MRI workflow which integrates hyperpolarized 13C imaging of metabolism and extracellular pH with [18F]FMISO PET to characterize hypoxia, acidosis, and metabolic reprogramming in feline sarcoma.
Martin Grashei, Tanja Groll, Stephanie Kahl, Silke Baer, Elisabeth Bliemsrieder, Frits H. A. van Heijster, Andre Wendlinger, Pascal Wodtke, Jorge Cabello, Susan Notohamiprodjo, Christian Lohrmann, Markus Schwaiger, Wolfgang A. Weber, Katja Steiger, Andrea Meyer‐Lindenberg, Johannes Hirschberger, Christine Baumgartner, Franz Schilling   +17 more
wiley   +1 more source

Multifunctional Ionic Liquid Enabling Cation Homogenization and Lead Chelation for Pure‐Iodide Wide‐Bandgap Perovskite Solar Cells

Advanced Science, EarlyView.
This work presents a multifunctional ionic liquid, [SO3H‐PMIm][OTf], that addresses A‐site cation inhomogeneity and lead toxicity in pure‐iodide wide‐bandgap perovskite solar cells. The additive enables homogeneous cation distribution, achieving 22.02% efficiency with 90% retention after 3000 h and reducing lead leakage by over 58%, thereby ...
Kai Wu, Lei Yang, Guoqing Du, Xin Wang, Jiali Wei, Tiantian Li, Pengfei Zhang, Xiaodan Zhang, Fuhua Hou   +8 more
wiley   +1 more source

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

Hepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai, Takahiro Kodama, Kazuki Maesaka, Shoichiro Tange, Daisuke Motooka, Yutaka Suzuki, Yasuyuki Shigematsu, Kentaro Inamura, Yoshihiro Mise, Akio Saiura, Yoshihiro Ono, Yu Takahashi, Yota Kawasaki, Satoshi Iino, Shogo Kobayashi, Masashi Idogawa, Takashi Tokino, Tomomi Hashidate‐Yoshida, Hideo Shindou, Masanori Miyazaki, Yasuharu Imai, Satoshi Tanaka, Eiji Mita, Kazuyoshi Ohkawa, Hayato Hikita, Ryotaro Sakamori, Tomohide Tatsumi, Hidetoshi Eguchi, Eiichi Morii, Tetsuo Takehara   +29 more
wiley   +1 more source

The CSI multimedia architecture

IEEE Transactions on Very Large Scale Integration (VLSI) Systems, 2005
An instruction set extension designed to accelerate multimedia applications is presented and evaluated. In the proposed complex streamed instruction (CSI) set, a single instruction can process vector data streams of arbitrary length and stride and combines complex memory accesses (with implicit prefetching), program control for vector sectioning, and ...
Cheresiz, D. (author), Juurlink, B. (author), Vassiliadis, S. (author), Wijshoff, H.A.G. (author)   +3 more
openaire   +4 more sources

Low Threshold Vertical Cavity Surface Emitting Lasers Based on CsPbI3 Thin Films

Advanced Science, EarlyView.
The first vertical‐cavity surface‐emitting laser (VCSEL) based on CsPbI3 thin films is fabricated by planar hot pressing. By optimizing the cavity design through optical gain assessment and rigorous coupled‐wave analysis, the VCSEL achieved an exceptionally low lasing threshold of 2.8 µJ cm−2.
Naho Kurahashi, Maximilian Schiffer, Cedric Kreusel, Christian Tückmantel, Ahmed Kadid, Habib Ur Rehman, Florian Gaschler, René Anfang, Christopher Knoth, Maximilian Buchmüller, Patrick Görrn, Thomas Riedl   +11 more
wiley   +1 more source

Center for Strategic and International Studies (CSIS)

, 2014
For over 50 years, the Center for Strategic and International Studies (CSIS) has developed practical solutions to the world’s greatest challenges. As we celebrate this milestone, CSIS scholars continue to provide strategic insights and bipartisan policy ...
CSIS
core  

Balancing Crystallization Kinetics and Lattice Strain Enables Thermally Stable Slot‐Die‐Coated Narrow‐Bandgap Perovskite Solar Cells

Advanced Science, EarlyView.
Unbalanced crystallization in mixed Sn‐Pb perovskites causes film defects and instability. CsPbI3 nanocrystals serve as nucleation seeds to regulate growth during slot‐die coating. Resulting solar cells retain 80% efficiency after nine thermal cycles. Operando GIWAXS confirms suppressed microstrain and lattice distortion, demonstrating that synergistic
Xiaojing Ci, Altantulga Buyan‐Arivjikh, Xiongzhuo Jiang, Simon A. Wegener, Christoph G. Lindenmeir, Lixing Li, Thomas Baier, Matthias Schwartzkopf, Sarathlal Koyiloth Vayalil, Kun Sun, Peter Müller‐Buschbaum   +10 more
wiley   +1 more source

Polarity‐Controlled Coexistence of Electrochemical Metallization and Valence Change Mechanisms in a Unified Metal Halide Perovskite Memristor

Advanced Science, EarlyView.
Electrochemical metallization and valence change mechanisms are shown to coexist within a single metal halide perovskite memristor, selectively activated by simply reversing the electroforming voltage polarity. Ag‐driven switching delivers low operating voltages and high endurance, while intrinsic ion migration yields superior retention and resistance ...
Ismael Fernandez‐Guillen, Omar E. Solis, Pablo F. Betancur, Rafael Abargues, Pablo P. Boix   +4 more
wiley   +1 more source