Results 41 to 50 of about 1,166 (95)

Vascular inflammaging: Endothelial CEACAM1 expression is upregulated by TNF‐α via independent activation of NF‐κB and β‐catenin signaling

open access: yesAging Cell, Volume 24, Issue 2, February 2025.
Early response: TNF‐α activates NF‐κB signaling by IKK‐induced degradation of the inhibitor of nuclear factor kappa B (IκB). Released NF‐κB translocates into the nucleus and upregulates CEACAM1 expression detectable after 24 h of TNF‐α stimulation. Delayed response: TNF‐α‐induced adherens junction disassembly releases β‐catenin, promoting its cytosolic
Lisa Götz   +6 more
wiley   +1 more source

Using Similarity Distance Measures for Multiclass Damage Detection in Dynamically Monitored Structures

open access: yesStructural Control and Health Monitoring, Volume 2025, Issue 1, 2025.
Domain adaptation (DA) techniques have recently been developed as a promising approach to enhance the performance of structural damage classification algorithms. Unlike traditional methods, DA imposes fewer constraints on the nature and completeness of datasets, although its effectiveness largely depends on the similarity between the datasets used for ...
Alessio Crocetti   +3 more
wiley   +1 more source

Chronic β3‐AR stimulation activates distinct thermogenic mechanisms in brown and white adipose tissue and improves systemic metabolism in aged mice

open access: yesAging Cell, Volume 23, Issue 12, December 2024.
(1) Chronic β3‐adrenergic agonist treatment improves systemic metabolism in aged mice. (2) Chronic β3‐adrenergic agonist activates futile lipid cycling and increases energy expenditure in the WAT of aged mice. (3) Lipolytic stimulation and futile lipid cycling are potential therapeutic targets to improve age‐related metabolic dysfunction.
Duraipandy Natarajan   +13 more
wiley   +1 more source

Postquantum Br\`{e}gman relative entropies and nonlinear resource theories

open access: yes, 2019
We introduce the family of postquantum Br\`{e}gman relative entropies, based on nonlinear embeddings into reflexive Banach spaces (with examples given by reflexive noncommutative Orlicz spaces over semi-finite W*-algebras, nonassociative L$_p$ spaces ...
Kostecki, Ryszard Paweł
core  

Analyzing perturbations in phyllotaxis of Arabidopsis thaliana [PDF]

open access: yes, 2010
International audienceVascular plants produce new organs at the tip of the stem in a very organized fashion. This patterning process occurs in small groups of stem cells, the so-called shoot apical meristems (SAM), and generates regular patterns called ...
Besnard, Fabrice   +5 more
core   +2 more sources

Connectivity Loss in Experimental Pond Networks Leads to Biodiversity Loss in Microbial Metacommunities

open access: yesGlobal Change Biology, Volume 30, Issue 12, December 2024.
In an outdoor mesocosm experiment, we studied the effects of habitat‐network fragmentation (i.e., the loss of connectivity between habitats) on planktonic prokaryote and microeukaryote communities. Connectivity loss resulted in a decrease of both local and regional diversity and reduced the survival probability in microeukaryotes, while prokaryotes ...
Beáta Szabó   +9 more
wiley   +1 more source

Aging human abdominal subcutaneous white adipose tissue at single cell resolution

open access: yesAging Cell, Volume 23, Issue 11, November 2024.
This study performed full‐length snRNA‐Seq and histological analyses on white adipose tissue (WAT) from 10 younger and 10 older individuals split evenly for sex and balanced for body mass index. We highlight that aging WAT is associated with adipocyte hypertrophy, increased proportions of lipid‐associated macrophages and mast cells, and an upregulation
K. L. Whytock   +11 more
wiley   +1 more source

Income Distributions and Decomposable Divergence Measures [PDF]

open access: yes
Inequality indices (i) evaluate the divergence between the income distribution and the hypothetical situation where all individuals have the mean income and (ii) are unambiguously reduced by a Pigou-Dalton progressive transfer.
Brice Magdalou, Richard Nock
core  

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