Results 171 to 180 of about 185,880 (279)

Conduction System Pacing Improved Cardiac Functions, Myocardial Work and Functional Capacity in Heart Failure with Reduced Ejection Fraction and Right Bundle Branch Block. [PDF]

J Clin Med
Tóth AZ, Nagy L, Jenei C, Ráduly AP, Sándorfi G, Szabó KM, Kiss A, Nagy LT, Szilágyi GI, Csanádi Z.   +9 more
europepmc   +1 more source

Structural investigation of human U6 snRNA recognition by spliceosomal recycling factor SART3 RNA recognition motifs

The FEBS Journal, EarlyView.
Human SART3 has two RRM domains to engage with U6 snRNA for spliceosome recycling. This study reports solution structures of SART3 RRM domains and investigates the interaction between RRM and U6 snRNA. SART3 binds to the asymmetric bulge of U6 snRNA as a dimer via conserved positively charged surfaces.
Iktae Kim, Kyeong‐Mi Bang, So Young An, Changkon Park, Ji‐Yeon Shin, Youngim Kim, Hyun Kyu Song, Jeong‐Yong Suh, Nak‐Kyoon Kim   +8 more
wiley   +1 more source

Exploring organic chemical space for materials discovery using crystal structure prediction-informed evolutionary optimisation. [PDF]

Nat Commun
Johal J, Day GM.
europepmc   +1 more source

The ALS‐associated E425K mutation uncouples DNAJC7 from the Hsp70 chaperone cycle

The FEBS Journal, EarlyView.
DNAJC7 is a J‐domain protein that plays a key role in protein quality control by regulating Hsp70 activity and preventing protein aggregation. We find that the ALS‐associated E425K mutation in DNAJC7 disrupts productive interaction and activation of Hsp70, thereby blocking the transfer and refolding of client proteins such as TDP‐43.
Bar Elmaleh, Ofrah Faust, Rina Rosenzweig   +2 more
wiley   +1 more source

Lightweight deep learning technology for high quality development and intelligent transformation of sports under DeepLabV3 CSP Darknet53 model. [PDF]

Sci Rep
Zhang J.
europepmc   +1 more source

Redox environment modulates aggregation of ataxin‐3 in vitro — Implications for drug screening of cysteine‐rich proteins

The FEBS Journal, EarlyView.
Redox environment modulates in vitro aggregation of Ataxin‐3, the protein implicated in spinocerebellar ataxia type 3. Reducing conditions stabilize native monomers and prevent aggregation, whereas oxidative conditions promote the formation of non‐native conformers and disulfide‐linked oligomers within the Josephin domain (JD).
Martyna Podlasiak, Martina Sollazzo, Elisa Monaca, Raffaele Sabbatella, Maria Agnese Morando, Oleg Chertkov, Laura Puglisi, Martina Mascellino, Anna Fricano, Sandra Macedo‐Ribeiro, Caterina Alfano   +10 more
wiley   +1 more source

Basic Physicochemical Properties of Pectin from Underutilized Chili Peppers Subjected to Different Heating Regimes. [PDF]

Foods
Ramos-Aguilar OP, Ruiz-Cruz S, Ornelas-Paz J, Ornelas-Paz JJ, Pérez-Martínez JD, Rios-Velasco C, Del-Toro-Sánchez CL, Márquez-Ríos E, Maya-Meraz IO, Ibarra-Junquera V, Escalante-Minakata P, Virgen-Ortiz JJ.   +11 more
europepmc   +1 more source

The Complex World of Toothpaste Diversity, Meeting Patient Clinical Needs. An Umbrella Review

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Background Amidst numerous recent advancements in toothpaste formulations and active ingredients, some clinicians may believe all toothpastes are similar despite differences in their active ingredients and corresponding clinical application.
Jeanie Suvan, Crystal Marruganti
wiley   +1 more source

Development and validation of a nomogram model for predicting postoperative complications of cesarean scar pregnancy based on clinical data. [PDF]

Front Med (Lausanne)
Cai P, Huang X, Zhang P.
europepmc   +1 more source

Genome and transcriptome‐based identification and expression profiling of chemosensory gene families across developmental stages and tissues in Sirex noctilio (Hymenoptera: Siricidae)

Insect Molecular Biology, EarlyView.
The first draft genome of Sirex noctilio was produced. Fifteen S. noctilio transcriptomes were sequenced to study chemosensory gene expression patterns. SnocOR16 and SnocSNMP1 displayed tissue‐ and sex‐specific expression patterns. Abstract The Sirex woodwasp (Sirex noctilio; Hymenoptera: Siricidae) is among the most destructive invasive pests ...
Alisa Postma, Leandri Klynsmith, Tuan A. Duong, Jeremy Dean Allison, Werner Smidt, Robert M. Waterhouse, Peter Lesny, Jan Philip Oeyen, Malte Petersen, Sebastian Martin, Shanlin Liu, Xin Zhou, Tanja Ziesmann, Alexander Donath, Christoph Mayer, Bernhard Misof, Oliver Niehuis, Ralph S. Peters, Lars Podsiadlowski, Martin P. A. Coetzee, Fourie Joubert, Bernard Slippers   +21 more
wiley   +1 more source