Results 111 to 120 of about 6,806,803 (376)

Radiomics and radiogenomics in intrahepatic cholangiocarcinoma

Исследования и практика в медицине
Purpose of the study. Analytical review and analysis of available literature on texture analysis of computed tomgraphy (CT) and magnetic resonance imaging (MRI) in noninvasive diagnosis of ICC and correlation with molecular genetic features and tumor ...
A. D. Smirnova, G. G. Karmazanovsky, E. V. Kondratyev, N.  A. Karelskaya, V. N. Galkin, A.  Yu. Popov, B. N. Gurmikov, D. V. Kalinin   +7 more
doaj   +1 more source

Cerebral Microbleeds in a Stroke Prevention Clinic

Diagnostics, 2019
The objective of this study was to assess the effectiveness of a stroke clinic in stroke prevention and progression of cerebral microbleeds (CMB). We conducted a retrospective observational study of patients who visited a stroke clinic between January ...
A-Hyun Cho, Lara Wadi, Daniel Chow, Peter Chang, David Floriolli, Krunal Shah, Annlia Paganini-Hill, Mark Fisher   +7 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

From routine to ruin: an astonishing computed tomography scan reveals catastrophic Ludwig’s angina and necrotizing mediastinitis after a simple dental procedure

European Journal of Case Reports in Internal Medicine
Ludwig’s angina is a rare, life-threatening cellulitis of the submandibular space, if unchecked, can rapidly progress to severe complications such as necrotizing mediastinitis, a condition with significant morbidity and mortality. We report the case of a
Amer Abu-Shanab, Anoohya Vangala, Zain Albdour, Hamzeh Nasr, Malay Rathod, Doantrang Du   +5 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Does total hip arthroplasty benefit patients with minimal radiological osteoarthritis?

Bone & Joint Open
Aims: The effectiveness of total hip arthroplasty (THA) for patients with no or minimal radiological signs of osteoarthritis (OA) is unclear. In this study, we aimed to: 1) assess the outcome of such patients; 2) identify patient comorbidities and CT or
Kartik Logishetty, Jeroen C. F. Verhaegen, Shannon Tse, Tim Maheswaran, Max Fornasiero, Hariharan Subbiah Ponniah, Jonathan B. Hutt, Johan D. Witt   +7 more
doaj   +1 more source

Diagnostic test interpretation and referral delay in patients with interstitial lung disease. [PDF]

, 2019
BACKGROUND:Diagnostic delays are common in patients with interstitial lung disease (ILD). A substantial percentage of patients experience a diagnostic delay in the primary care setting, but the factors underpinning this observation remain unclear.
Adegunsoye, Ayodeji, Boctor, Noelle, Chung, Jonathan H, DiGeronimo, Ryan, Kadoch, Michael, Lafond, Elyse, Oldham, Justin M, Pan, Isabella, Pritchard, David, Pugashetti, Janelle Vu, Sarma, Nandini, Strek, Mary   +11 more
core   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Analysis of Accuracy Related Factors in Photon Counting X-ray CT Energy Imaging

CT Lilun yu yingyong yanjiu
Multi-energy spectrum imaging with photon counting detectors has become the focus of X-ray imaging. In this study, the Geant4 simulation software was used to generate the energy spectrum of the ray source, obtaining high-low energy spectra of different ...
Jiasheng CAO, Baolei LI
doaj   +1 more source