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Spectrophotometric study on binding of 2-thioxanthone acetic acid with ct-DNA

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018
Thioxanthone and its derivatives are the most remarkable molecules due to their vast variety of application such as radiation curing that is, until using them as a therapeutic drug. Therefore, in this study it was intended to use 2-Thioxanthone acetic acid with and without NaCl in Tris HCl buffer solution (pH:7.0) to represent the interaction with ct ...
Ataci, Neşe   +2 more
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Photophysics of ethidium bromide complexed to ct-DNA: a maximum entropy study

Biophysical Chemistry, 1998
Time-integrated and time-resolved fluorescence spectroscopies have been used to probe the photophysical properties of ethidium bromide (Eb) complexed to calf thymus DNA (ct-DNA). Fluorescence decay profiles are obtained using the technique of time-correlated single photon counting (TCSPC), and subsequently analysed using conventional sum-of-exponential
C D, Byrne, A J, de Mello
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Iodinated contrast media increase DNA damage during CT

2008
Purpose: DNA double-strand breaks (DSBs) are among the most significant genetic lesions introduced by ionising radiation. Theoretically, iodinated contrast agents could enhance ionisation in tissues and therefore elevate DNA damage level.
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Simultaneous effect of cadaverine and osmolytes on ct-DNA thermal stability

Thermochimica Acta, 2004
Abstract In the real cellular conditions, the biological macromolecules, as DNA and proteins, live in high concentrations of biomolecules, salts and so on. In particular organisms and cellular systems, which have adapted to extreme environmental conditions, accumulate particular organic solutes, known as osmolytes, at moderate to high concentrations ...
PETRACCONE, LUIGI   +5 more
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Circulating tumor (ct)-DNA alterations in patients with testicular germ tumors.

Journal of Clinical Oncology, 2019
e16063 Background: Testicular germ cell tumors (GCT) infrequently harbor somatic mutations. ctDNA assay allows the noninvasive genomic profiling of malignancies and may assist with understanding molecular evolution of resistance. To our knowledge, ctDNA genomic alterations observed in in testicular GCTs have not been heretofore described.
Amin Nassar   +8 more
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Assessment of organotins against the linoleic acid, glutathione and CT-DNA

Inorganica Chimica Acta, 2014
Abstract The already known di-n-butyltin(IV) complex of the chiral anti-inflammatory drug naproxen (Hnapr) of formula [(n-Bu-)2Sn(nap)2] (1), was re-synthesized here with an alternative method and it was used for the assessment of organotins towards the linoleic acid which is located in the cell membrane, the intracellular glutathione and the nuclear
Banti, Christina N.   +13 more
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Radiation induced DNA double strand breaks undergoing PET/CT examinations.

2011
Purpose: Background: Physical or mathematical dosimetry approaches in clinical routine can not include a measure of biological x-ray interactions. In patients undergoing combined positron emission tomography (PET) and computed tomography (CT) contribution of...
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Spectral and Electrochemical Investigation of Intercalations of Adrenaline and CT‐DNA

Chinese Journal of Chemistry, 2003
AbstractA strong interaction between double stranded calf‐thymus DNA (ds‐DNA) and adrenaline in solution, but no interaction between single stranded calf‐thymus DNA (ss‐DNA) and adrenaline was observed by the use of UV‐visible spectroscopy and voltametric techniques. It is suggested that the interaction leads to an intercalation of adrenaline molecules
Sai‐Jing Zheng, Xiang‐Qin Lin
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Voltammetric Behavior of Dopamine at ct-DNA Modified Carbon Fiber Microelectrode

Microchimica Acta, 2003
A sub-micrometer thin-layer DNA modified carbon fiber microcylinder electrode was prepared by electrodeposition of ct-DNA at 1.5 V (vs. Ag/AgCl). The voltammetric behavior of dopamine (3-hydroxytyramine) was investigated at the modified electrode. It was found that the modified electrode exhibits a highly electrocatalytic activity toward dopamine ...
Xiang-Qin Lin   +2 more
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Radiation induced DNA double-strand breaks in cardiac CT

2008
Purpose Methods and Materials Results ...
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