Results 31 to 40 of about 11,382 (203)

A New Nail in the CTCL Coffin [PDF]

Journal of Investigative Dermatology, 2006
The impact of immunotherapy on the natural progression of cutaneous T-cell lymphoma (CTCL), particularly the mycosis fungoides and Sézary syndrome variants, has been based on our evolving understanding of the disease's immunobiology.
openaire   +2 more sources

The stones on the perimeter of the circle. Disquisitions on Roland Barthes’ Camera lucida and its possible connections with Inés Ulanovsky’s Fotos tuyas

Estudios de Teoría Literaria, 2020
In the studies on image and photography, Camera lucida of Roland Barthes is usually considered a milestone, not only for the appropriation of some notions but for the reactions and criticisms that it provoked.
Bruno Crisorio, Silvina Sánchez
doaj  

Novel cell adhesion/migration pathways are predictive markers of HDAC inhibitor resistance in cutaneous T cell lymphomaResearch in context

EBioMedicine, 2019
Background: Treatment for Cutaneous T Cell Lymphoma (CTCL) is generally not curative. Therefore, selecting therapy that is effective and tolerable is critical to clinical decision-making. Histone deacetylase inhibitors (HDACi), epigenetic modifier drugs,
Jared M. Andrews, Jennifer A. Schmidt, Kenneth R. Carson, Amy C. Musiek, Neha Mehta-Shah, Jacqueline E. Payton   +5 more
doaj   +1 more source

Cutaneous T-cell lymphoma in erythrodermic cases may be suspected on the basis of scalp examination with dermoscopy

Scientific Reports, 2021
Erythrodermic variants of cutaneous T-cell lymphoma (CTLC) are one of the case of erythroderma. The aim of the study was to assess the value of scalp dermoscopy in differentiation between erythrodermic CTCL, psoriasis, and atopic dermatitis.
Adriana Rakowska, Magdalena Jasińska, Mariusz Sikora, Joanna Czuwara, Patrycja Gajda-Mróz, Olga Warszawik-Hendzel, Małgorzata Kwiatkowska, Anna Waśkiel-Burnat, Małgorzata Olszewska, Lidia Rudnicka   +9 more
doaj   +1 more source

New JAK3-INSL3 Fusion Transcript—An Oncogenic Event in Cutaneous T-Cell Lymphoma

Cells, 2023
Constitutively activated tyrosine kinase JAK3 is implicated in the pathogenesis of cutaneous T-cell lymphomas (CTCL). The mechanisms of constitutive JAK3 activation are unknown although a JAK3 mutation was reported in a small portion of CTCL patients. In
Loka Reddy Velatooru, Cheng Hui Hu, Pedram Bijani, Xiaohong Wang, Pierr Bojaxhi, Hao Chen, Madeleine Duvic, Xiao Ni   +7 more
doaj   +1 more source

Blood and skin-derived Sezary cells: differences in proliferation-index, activation of PI3K/AKT/mTORC1 pathway and its prognostic relevance [PDF]

, 2019
Sézary syndrome (SS) is a rare and aggressive variant of Cutaneous T-Cell Lymphoma characterized by neoplastic distribution mainly involving blood, skin, and lymph-node.
Benucci, Roberto, Bresin, Antonella, Cantonetti, Maria, Caprini, Elisabetta, Cristofoletti, Cristina, D’Atri, Stefania, Frezzolini, Alessandra, Helmer Citterich, Mauro, Monopoli, Alessandro, Monzo, Francesca, Narducci, Maria Grazia, Passarelli, Francesca, Picchio, Maria Cristina, Picozza, Mario, Russo, Giandomenico, Scala, Enrico   +15 more
core   +1 more source

Expanding and expounding the genomic map of CTCL [PDF]

Blood, 2017
Background: Acute myeloid leukemia (AML) is a highly heterogenous condition. Current risk stratification based on cytogenetics and molecular genetic markers at point of diagnosis is used to predict treatment response and relapse risk. The conventional way of defining complete remission (CR) is based on morphological identification of ≤5% blasts seen ...
Anjali Mishra, Pierluigi Porcu
openaire   +2 more sources

Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma [PDF]

, 2015
Aberrant activation of Janus kinase-3 (Jak3) and its key down-stream effectors, Signal Transducer and Activator of Transcription-3 (STAT3) and STAT5, is a key feature of malignant transformation in cutaneous T-cell lymphoma (CTCL).
Bonefeld, Charlotte M., Fredholm, Simon, Geisler, Carsten, Gniadecki, Robert, Iversen, Lars, Jønson, Lars, Kopp, Katharina L., Krejsgaard, Thorbjørn, Lindahl, Lise M., Litvinov, Ivan V., Mongan, Nigel P., Nastasi, Claudia, Odum, Niels, Petersen, David L., Sasseville, Denis, Sibbesen, Nina A., Wasik, Mariusz A., Willerslev-Olsen, Andreas, Woetmann, Anders   +18 more
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Bexarotene Reduces Production of CCL22 From Tumor-Associated Macrophages in Cutaneous T-Cell Lymphoma

Frontiers in Oncology, 2019
Bexarotene is a third-generation retinoid X receptor-selective retinoid that has been approved for use in the treatment of both early and advanced cutaneous T-cell lymphoma (CTCL).
Kayo Tanita, Taku Fujimura, Yota Sato, Chunbing Lyu, Yumi Kambayashi, Dai Ogata, Satoshi Fukushima, Azusa Miyashita, Hideki Nakajima, Motoki Nakamura, Akimichi Morita, Setsuya Aiba   +11 more
doaj   +1 more source

The Cosmic Microwave Background and Particle Physics [PDF]

, 1999
In forthcoming years, connections between cosmology and particle physics will be made increasingly important with the advent of a new generation of cosmic microwave background (CMB) experiments. Here, we review a number of these links.
Arthur Kosowsky, Bardeen JM, Bond JR, Burigana C, Corey BE, Cronin JW, Danese L, Dicke RH, Fang LZ, Fierz M, Fixsen DJ, Hawking SW, Hill CT, Ivanchik AV, Jones BJT, Kibble TWB, Kinney W, Kneissl R, Kofman L, Kofman LA, Kolb EW, Kuzmin VA, Lyth DH, Marc Kamionkowski, Milaneschi E, Mukhanov V, Novikov ID, Peebles PJE, Peebles PJE, Perlmutter S, Sakharov AD, Sarkar S, Shafer RA, Sokolov IY, Starobinsky AA, Starobinsky AA, Sunyaev RA, Vilenkin A, Will CM, Witten EW, Zatsepin GT, Zeldovich YaB, Zeldovich YaB   +42 more
core   +2 more sources