Results 231 to 240 of about 147,964 (338)

Distinct by Design: Unraveling the Unique Clinical and Transcriptomic Identity of Juvenile Scleromyositis Overlap Compared to Juvenile Systemic Sclerosis and Juvenile Dermatomyositis: Implications for Care and Pathogenesis

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective To characterize clinical and transcriptomic differences in juvenile scleromyositis overlap (jOverlap) compared to juvenile systemic sclerosis (jSSc) and juvenile dermatomyositis (JDM), focusing on autoantibody profiles, organ involvement, treatment, and peripheral blood gene expression.
Amanda D. Robinson, Clare E. Pain, Gabrielle A. Morgan, Anwesha Sanyal, Srilakshmi Chaparala, Lauren M. Pachman, Kathryn S. Torok   +6 more
wiley   +1 more source

Ginsenoside RG3 and cantharidin synergistically suppress the progression of hepatocellular carcinoma via targeting the PRMT1-SREBF1 axis-mediated lipid metabolism. [PDF]

J Transl Med
Wang Y, Yuan H, Yu Y, Gou X, Wang Z, Zhou Z, Wang Z, Yan W, Wang H, Yan J.   +9 more
europepmc   +1 more source

Circulation and Variability in the Tropical Atlantic METEOR Cruise No. 62, Leg 2 from Fortaleza, Brazil to Recife, Brazil August 8 to August 31, 2004 [PDF]

, 2005
Affler, Karina, Brandt, Peter, Dengler, Marcus, Dispert, Astrid, Dombrowsky, Uwe, Ferreira, Maria, Fischer, Jürgen, Funk, Andreas, Hummels, Rebecca, Mahmud, Nadira, Maluf, Vladimir Costa, Müller, Mario, Papenburg, Uwe, Schafstall, Jens, Stramma, Lothar, Truscheit, Thorsten, Veleda, Doris, Weddige, Phillip, Zantopp, Rainer J.   +18 more
core  

Directed Functionalization of Recombinant Spider Silk Nonwoven Membranes with Antibodies Using Non‐Canonical Amino Acids

Advanced Materials, Volume 38, Issue 14, 6 March 2026.
A recombinant spider silk protein was functionalized by incorporating genetically encoded bio‐orthogonal reactive azido‐groups. The azido‐functionalized proteins were produced in a scalable biotechnological process, and particles, films, as well as nanofibers were established as anchorage for fully functional antibodies via site‐specific bio‐orthogonal
Claudia Lacombe, Charlotte Leonhardt, Martin Humenik, Birgit Wiltschi, Thomas Scheibel   +4 more
wiley   +1 more source

Tho1 and MOS11 promote nucleic acid double-strand unwinding by facilitating DEAD-box helicase oligomerization. [PDF]

Nucleic Acids Res
Becker F, Miosga MB, Mannan M, Bettenworth V, Steinchen W, Sträßer K, Friedhoff P.   +6 more
europepmc   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

Microenvironmental niches dictate divergent fibroblast fates in reversible versus progressive lung fibrosis. [PDF]

EBioMedicine
Song L, Yang Y, Fu Y, Liu Y, Li Q, Zheng M, Yao C, Song D, Su R, Chen W, Chen J, Chen H, Xie L.   +12 more
europepmc   +1 more source

WHP Cruise Summary Information of section A16C [PDF]

, 1989
Talley, Lynne
core  

DNMT2‐m5C‐ACLY Axis Promotes Lenvatinib Resistance in Hepatocellular Carcinoma Through Histone Acetylation‐Mediated Notch Pathway

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Lenvatinib resistance poses a major challenge in advanced hepatocellular carcinoma (HCC). This study reveals that DNMT2 upregulation is a key driver, which stabilizes ACLY mRNA via m5C modification and activates the Notch signaling pathway. Crucially, combining ACLY inhibitors with lenvatinib overcomes resistance and suppresses tumors, offering a ...
Shiguang Yang, Jie Li, Shengwei Mao, Xuhui Zhao, Douwaner Liu, Jiafeng Chen, Jialu Fu, Yichao Bu, Xiaoling Wu, Shaoqing Liu, Qifeng Yu, Qiongzhu Dong, Zheng Tang, Yuan Fang, Yinghong Shi   +14 more
wiley   +1 more source

Clinical characteristics of high-altitude interstitial lung disease: a two-center, retrospective, observational study. [PDF]

BMC Pulm Med
Zhou L, Zhu M, Chen L, Wang Y, Xu L, Liu J, Chen L, Tuo Y, Meilang Q, Luo F.   +9 more
europepmc   +1 more source