Results 251 to 260 of about 147,964 (338)

Effects of High‐ and Low‐Fat Meals on the Bioavailability and Pharmacokinetics of Votoplam, a HTT Gene Splicing Modifier

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 3, March 2026.
Abstract Votoplam is a novel, orally bioavailable, small molecule HTT gene splicing modifier that is being developed for the treatment of Huntington's disease. This was a single dose, open‐label, two‐period, crossover food effect study that evaluated the effect of high‐ and low‐fat meals on 20 mg votoplam in healthy participants. There was a washout of
Lucy Lee   +5 more
wiley   +1 more source

Cardiovascular Functioning Features in Individuals with Connective Tissue Dysplasia Engaged in Sports for the Disabled. [PDF]

open access: yesSports (Basel)
Vinokurova K   +6 more
europepmc   +1 more source

Deep refuges: the distribution of marine fish in warming subtropics

open access: yesEcography, Volume 2026, Issue 3, March 2026.
In light of global climate change, identifying critical marine habitats and conserving them is essential. Marine conservation planning recommends designating cooler habitats as marine protected areas. The ‘deep‐reef refugia' hypothesis suggests that deeper, suitable habitats may allow species to undergo the evolutionary changes necessary to adapt to ...
Anat Tsemel   +7 more
wiley   +1 more source

Matrix metalloproteinases levels in induced sputum in IPF and CTD-ILD. [PDF]

open access: yesBMC Pulm Med
Zhang F   +10 more
europepmc   +1 more source

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