Results 261 to 270 of about 146,534 (333)

Saccharin Aggravates Eosinophilic Esophagitis via MAPK3 Interaction: A Network Toxicology and Machine Learning Study With SPR Analysis

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
This study provides a novel molecular perspective on the role of dietary factors in EoE pathogenesis. We establish saccharin as a key aggravating factor for EoE and highlight MAPK3 as a compelling therapeutic target. Our findings suggest that controlling saccharin intake represents a direct and beneficial dietary management strategy for EoE.
Yuan Yang, Tao Guo, Peiyuan Li, Kangle Gao, Xufeng Ning, Lingshan Zhou, Weiwei Zhou, Bin Zeng   +7 more
wiley   +1 more source

Structural and functional insights into internal domain replacement in SpCas9 for protein engineering. [PDF]

Sci Rep
Kim S, Won H, Bae J, Kim J, Choi J, Richar H, Kim YG, Choi HJ.   +7 more
europepmc   +1 more source

Integrated Single Cell Spatial Analysis Reveals Dysregulated Basal Progenitor Cells in Ulcerative Colitis Pathogenesis: A Multi Omics Study

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Ulcerative colitis (UC), a chronic inflammatory bowel disease, causes persistent mucosal inflammation and epithelial dysfunction. Basal progenitor cells (BPCs), critical for intestinal regeneration and mucosal repair, exhibit altered behavior in UC.
Xiaopeng Chen, Chuiguo Huang, Zhuofeng Wen, Weixuan Liang, Haobin Zhou, Zhiyi Zhou, Songan Li, Jianyang Guo, Naijun Yuan, Wanzhe Liao   +9 more
wiley   +1 more source

Identification of Co-Diagnostic Genes and Potential Therapeutic Targets for Asthma and Sepsis Through Mendelian Randomization and Immune Infiltration Analysis. [PDF]

J Asthma Allergy
Chen C, Li X, Zhang X, Hu M, Yang M, Yuan Z, Yao S, Qin S, Qin Y, Xiao Y.   +9 more
europepmc   +1 more source

Size of planktic foraminifera at CTD station PS55/066

, 2001
Elena Stangeew
openalex   +1 more source

Modelling Stream Temperature in Subtropical Headwaters: Performance of Empirical Air‐Stream Relationships in Southern Brazil

Hydrological Processes, Volume 40, Issue 1, January 2026.
Stream temperature variability was assessed in subtropical Brazilian headwaters using linear and nonlinear air–water models. Backward moving average regressions captured delayed thermal responses driven by water's thermal inertia, with intra‐daily fluctuations typically below 1°C.
Geovana Thaís Colombo Fernandes, Michael Männich   +1 more
wiley   +1 more source

EEG power modulation in the sensorimotor regions is critical to motor tic suppression. [PDF]

Front Psychiatry
Miyakoshi M, Jurgiel J, Dillon A, Piacentini J, Makeig S, Loo SK.   +5 more
europepmc   +1 more source

CTD (Conductivity, Temperature, Depth) data collected during research cruise AE2416 using a SeaBird SBE-911+ instrument system onboard the platform RV Atlantic Explorer

Rolling Deck to Repository
openalex   +1 more source

Clinical Characteristics of Patients With Anti‐Signal Recognition Particle Antibody: A Cohort Study

Immunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.
ABSTRACT Background Anti‐signal recognition particle (anti‐SRP) antibodies are myositis‐specific autoantibodies associated with immune‐mediated necrotizing myopathy. This study was undertaken to better understand how patients with anti‐SRP antibodies have been managed at our tertiary centre and to assess the spectrum of clinical features and outcomes ...
Ameen Jubber, Maumer Durrani, Abdullah Almayahi, Kehinde Sunmboye   +3 more
wiley   +1 more source

Social memory maintenance relies on social interaction-induced proteolytic products of neuroligin 1. [PDF]

Signal Transduct Target Ther
Liu A, Li X, Zhuang M, Ren Q, Zhang J, Lv D, Wu M, Bian X, Zhu C, Yang X, Li M, Wang Y, Jia Z, Xie W.   +13 more
europepmc   +1 more source