Results 271 to 280 of about 147,964 (338)

Daidzein Ameliorate Hyperuricemia by Upregulating ABCG2 Expression via Activation of PPARγ and PI3K/AKT Pathways

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
Hyperuricaemia is a chronic metabolic disorder arising from impaired purine metabolism, exhibiting marked gender disparities in its prevalence. Daidzein, possessing oestrogen‐like effects, promotes uric acid excretion and improves hepatic and renal function, thereby presenting potential utility as an adjunctive therapeutic agent for hyperuricaemia ...
Zicheng Zhu   +9 more
wiley   +1 more source

Pulmonary Venous Vasculopathy in Connective Tissue Disease-Associated Pulmonary Arterial Hypertension With Reduced Diffusion Capacity for Carbon Monoxide. [PDF]

open access: yesPulm Circ
Fujisaki S   +10 more
europepmc   +1 more source

Vitamin D Attenuates Inflammation and Mitochondrial Dysfunction in Experimental Models Relevant to Connective Tissue Disease–Associated Pulmonary Arterial Hypertension

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
Mechanism study of VD mediated inflammatory and mitochondrial homeostasis in early PAH progression. ABSTRACT Vitamin D (VD) deficiency is prevalent in chronic inflammatory disorders and has been implicated in cardiopulmonary diseases. This study investigated whether VD, as a nutritional factor, modulates inflammatory and mitochondrial homeostasis in ...
Yansheng Jin   +4 more
wiley   +1 more source

Identification of receptor-binding domains of Bacteroidales antibacterial pore-forming toxins. [PDF]

open access: yesJ Biol Chem
Borgini S   +7 more
europepmc   +1 more source

Study on the Potential Molecular Mechanisms of Sodium Dehydroacetate (Na‐DHA) Interfering With Bone Metabolism and Inducing Osteoporosis Based on Network Toxicology, Molecular Docking, and In Vitro Experimental Validation

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
The main workflow and core design concept of the current study. ABSTRACT Sodium Dehydroacetate (Na‐DHA), a widely used food additive, has raised concerns about the chronic health risks associated with long‐term exposure. However, the potential impact of Na‐DHA on bone metabolism, its contribution to osteoporosis risk, and the specific molecular ...
Weihong Qian   +6 more
wiley   +1 more source

Radiation-response in <i>Deinococcus</i> bacteria: characterization of the transient IrrE-DdrO heterodimer complex. [PDF]

open access: yesFEMS Microbes
Reuzeau A   +8 more
europepmc   +1 more source

Repeated Episodes of GPP Induced by Respiratory Infections Are Mediated by Loss‐of‐Function IFIH1

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
ABSTRACT Background Generalized pustular psoriasis (GPP) is a severe and recurrent autoinflammatory disease that can be induced by a variety of factors. At present, its etiology and pathogenesis have not yet been fully elucidated. Upper respiratory tract infections are the main predisposing factor in children with GPP, and the MDA5 protein encoded by ...
Yaqin Liu   +5 more
wiley   +1 more source

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