Hyperuricaemia is a chronic metabolic disorder arising from impaired purine metabolism, exhibiting marked gender disparities in its prevalence. Daidzein, possessing oestrogen‐like effects, promotes uric acid excretion and improves hepatic and renal function, thereby presenting potential utility as an adjunctive therapeutic agent for hyperuricaemia ...
Zicheng Zhu +9 more
wiley +1 more source
Pulmonary Venous Vasculopathy in Connective Tissue Disease-Associated Pulmonary Arterial Hypertension With Reduced Diffusion Capacity for Carbon Monoxide. [PDF]
Fujisaki S +10 more
europepmc +1 more source
Mechanism study of VD mediated inflammatory and mitochondrial homeostasis in early PAH progression. ABSTRACT Vitamin D (VD) deficiency is prevalent in chronic inflammatory disorders and has been implicated in cardiopulmonary diseases. This study investigated whether VD, as a nutritional factor, modulates inflammatory and mitochondrial homeostasis in ...
Yansheng Jin +4 more
wiley +1 more source
Identification of receptor-binding domains of Bacteroidales antibacterial pore-forming toxins. [PDF]
Borgini S +7 more
europepmc +1 more source
Carbonate hardgrounds. - In: Ratmeyer, V., Hebbeln, D. & Shipboard Party: Report and Preliminary Results of RV Meteor Cruise M61-3 [PDF]
Noé, Sibylle
core
The main workflow and core design concept of the current study. ABSTRACT Sodium Dehydroacetate (Na‐DHA), a widely used food additive, has raised concerns about the chronic health risks associated with long‐term exposure. However, the potential impact of Na‐DHA on bone metabolism, its contribution to osteoporosis risk, and the specific molecular ...
Weihong Qian +6 more
wiley +1 more source
Radiation-response in <i>Deinococcus</i> bacteria: characterization of the transient IrrE-DdrO heterodimer complex. [PDF]
Reuzeau A +8 more
europepmc +1 more source
Oceanographic results from the VERTEX 5 particle-trap experiment across the California current May-July 1984 [PDF]
Broenkow, William W., Reaves, Richard E.
core
Repeated Episodes of GPP Induced by Respiratory Infections Are Mediated by Loss‐of‐Function IFIH1
ABSTRACT Background Generalized pustular psoriasis (GPP) is a severe and recurrent autoinflammatory disease that can be induced by a variety of factors. At present, its etiology and pathogenesis have not yet been fully elucidated. Upper respiratory tract infections are the main predisposing factor in children with GPP, and the MDA5 protein encoded by ...
Yaqin Liu +5 more
wiley +1 more source
A Lung Ultrasound-Integrated Clinical Model for Predicting Pulmonary Arterial Hypertension in Patients with Connective Tissue Disease-Associated Interstitial Lung Disease. [PDF]
Lian X +6 more
europepmc +1 more source

