Results 121 to 130 of about 424,490 (383)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Avaliação das atitudes das duas culturas em relação à aprendizagem da ciência

open access: yesRevista Iberoamericana de Educación, 2012
Este trabalho apresenta resultados obtidos de acordo com a avaliação das atitudes em relação à aprendizagem da ciência, a partir de estudantes pré-universitários, em início e fim da universidade e professores, todos vinculados ao cefet/rj.
Patrick de Miranda Antonioli   +3 more
doaj  

PERBANDINGAN KONFIGURASI TANGAN DAN PERGELANGAN TANGAN PADA PASIEN CARPAL TUNNEL SYNDROME DENGAN ORANG NORMAL [PDF]

open access: yes, 2015
Background : Most cases of Carpal Tunnel Syndrome are idiopathic. The dimensions of the hand and wrist is an important factor in the development of CTS. Aim : Knowing the difference of hand ratio and wrist ratio between CTS and normal people. Methods :
Prastiyo, Dian Andi, Widagda, I Made
core   +1 more source

Improved Collective Thomson Scattering measurements of fast ions at ASDEX Upgrade

open access: yes, 2013
Understanding the behaviour of the confined fast ions is important in both current and future fusion experiments. These ions play a key role in heating the plasma and will be crucial for achieving conditions for burning plasma in next-step fusion devices.
Jacobsen, A. S.   +14 more
core   +1 more source

CellLab-CTS 2015: continuous-time stochastic cellular automaton modeling using Landlab

open access: yes, 2016
. CellLab-CTS 2015 is a Python-language software library for creating two-dimensional, continuous-time stochastic (CTS) cellular automaton models. The model domain consists of a set of grid nodes, with each node assigned an integer state code that ...
G. Tucker   +6 more
semanticscholar   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Revisores del volumen 4

open access: yesCiencia, Tecnología y Salud, 2018
Revista Eunice CTS
doaj   +3 more sources

Crítica al experimento crucial: Michelson y la hipótesis del éter (1887- 1930). Algunas implicaciones para la enseñanza de la física (15/17 años)

open access: yesRevista Eureka sobre Enseñanza y Divulgación de las Ciencias, 2006
La discusión se basa en dos líneas argumentativas, respectivamente la caracterización de la noción de éter en las teorías preexistentes a las primeras mediciones interferométricas de Michelson como un término teórico ad hoc, preservado en la ...
A. Drewes, H. Palma
doaj  

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

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