Results 1 to 10 of about 25,329 (180)

Different approaches for transformation of mesenchymal stem cells into hepatocyte-like cells

Stem Cell Research & Therapy, 2020
Due to the prominent role of the liver in the body and detoxification, its functionality can be affected in an irreversible manner by diseases. This phenomenon renders the liver to stop working, leading to morbidity and mortality.
Afsoon Afshari, Sara Shamdani, Georges Uzan, Sina Naserian, Negar Azarpira   +4 more
doaj   +1 more source

Harnessing Polygenic Risk Scores to Refine Venous Thromboembolism Risk Stratification

European Journal of Haematology, EarlyView.
ABSTRACT Background Venous thromboembolism (VTE) is a major cause of morbidity in patients of all ages. Despite growing interest in polygenic risk scores (PRS) for VTE, their utility remains understudied. Our objective was to evaluate the independent impact of a PRS on VTE susceptibility in adults and children.
Katlyn G. McKay, Oliver S. Zhao, Samaya S. Badrieh, Lisa Bastarache, Xinnan Niu, Jing He, Prince J. Kannankeril, Jamie R. Robinson   +7 more
wiley   +1 more source

Academic Family Medicine's Response to CTSA [PDF]

The Annals of Family Medicine, 2007
The Institutional Clinical and Translational Science Awards (CTSAs) are the cornerstone of the National Institutes of Health Roadmap Initiative that intends to transform research by promoting new models of research and expanding research training for the future.
M. S. Johnson, A. Davis
openaire   +1 more source

Characteristic of a group of genes with low level of expression in the pancreas of rats under conditions of multi-day intermittent hypoxia influence

Patologìâ
In modern medical science great attention is paid to the clarification of the molecular mechanisms, which are the basis of adaptation to environmental factors of unusual origin and/or extraordinary strength.
T. V. Ivanenko, Yu. M. Kolesnyk, A. V. Abramov   +2 more
doaj   +1 more source

The Development of a Soft Robot Hand with Pin-Array Structure

Applied Sciences, 2019
This paper proposes a soft robot hand with pin-array structure and self-adaptive function, CTSA-II hand, where CTSA is the Cluster tube self-adaption.
Hong Fu, Wenzeng Zhang
doaj   +1 more source

Dolutegravir population pharmacokinetics in racially, sex‐ and age‐diverse and antiretroviral therapy‐experienced adults with HIV in the United States

HIV Medicine, EarlyView.
Abstract Objectives Dolutegravir (DTG) has been associated with weight gain in women with HIV, Black people with HIV and people with HIV60 years. This study aimed to characterise DTG population pharmacokinetics (PopPK) in a diverse population including these sub‐populations.
Adrian Khoei, Andrew Edmonds, Yen Chang, Catalina Ramirez, Mackenzie Vogan, Amanda Poliseno, Steven Wolinsky, Ken Ho, Todd T. Brown, Joseph B. Margolick, Jacquett Batson, Jennifer Hoffmann, Mark A. Marzinke, Mirjam‐Colette Kempf, Maria L. Alcaide, Joffi Effoe, Cecile D. Lahiri, Igho Ofotokun, Anandi N. Sheth, Stephen Gange, Audrey L. French, Bani Tamraz, Bradley E. Aouizerat, Phyllis C. Tien, Seble G. Kassaye, Jack DeHovitz, Kathryn Anastos, Kara W. Chew, Michelle Floris‐Moore, Julie B. Dumond   +29 more
wiley   +1 more source

Using the translational science benefits model to evaluate the impact of community-engaged programs

Journal of Clinical and Translational Science
Assessing the long-term impact of community-engaged research (CEnR) programs remains a significant challenge in translational science, such as those conducted by Clinical and Translational Science Awards (CTSAs). The Translational Science Benefits Model (
Stacey M. Gomes, Bridget Nolan Murphy, Monica J. Mitchell, Aaron Grant, Farrah M. Jacquez, Brittany L. Rosen, Lori E. Crosby   +6 more
doaj   +1 more source

What does team science look like across the CTSA consortium? A qualitative analysis of the Great CTSA Team Science Contest submissions

Journal of Clinical and Translational Science, 2021
Introduction: The Great CTSA Team Science Contest (GTSC) was developed to discover how Clinical and Translational Science Award (CTSA) hubs promote and support team science [1].
Clara M. Pelfrey, Ann S. Goldman, Deborah J. DiazGranados   +2 more
doaj   +1 more source

Lonergan, Decolonization and First Nations Peoples: An Apologetic from an Insider on the Outside

Modern Theology, EarlyView.
Abstract The purpose of this article is to respond critically to a research project initiated out of the Board of the Lonergan Research Institute that seeks to expose colonialist assumptions in Lonergan's thought. Some of the initiatives seek to link Lonergan with complicity in Canadian residential schools, spiritual violence, and cultural genocide ...
John D. Dadosky
wiley   +1 more source

Demographic composition of National Institutes of Health Clinical and Translational Science Awards (CTSA) Program principal investigators, scholars, and trainees

Journal of Clinical and Translational Science, 2023
Little has been published on the demographic composition of the clinical and translational science research workforce within the Clinical and Translational Science Awards (CTSA) Program despite the well-documented need for greater diversity in the ...
Mercedes Rubio, Heather L. Baker, Jamie Mihoko Doyle   +2 more
doaj   +1 more source