Results 61 to 70 of about 38,249 (207)

Characteristic of a group of genes with low level of expression in the pancreas of rats under conditions of multi-day intermittent hypoxia influence

Patologìâ
In modern medical science great attention is paid to the clarification of the molecular mechanisms, which are the basis of adaptation to environmental factors of unusual origin and/or extraordinary strength.
T. V. Ivanenko, Yu. M. Kolesnyk, A. V. Abramov   +2 more
doaj   +1 more source

Different approaches for transformation of mesenchymal stem cells into hepatocyte-like cells

Stem Cell Research & Therapy, 2020
Due to the prominent role of the liver in the body and detoxification, its functionality can be affected in an irreversible manner by diseases. This phenomenon renders the liver to stop working, leading to morbidity and mortality.
Afsoon Afshari, Sara Shamdani, Georges Uzan, Sina Naserian, Negar Azarpira   +4 more
doaj   +1 more source

Towards Principled Responsible Research and Innovation: Employing the Difference Principle in Funding Decisions [PDF]

, 2015
Responsible Research and Innovation (RRI) has emerged as a science policy framework that attempts to import broad social values into technological innovation processes whilst supporting institutional decision-making under conditions of uncertainty and ...
Brownlie Ian, De Waal Frans, Lanczkowski Guenter, Nussbaum Martha, Ozolina Zaneta, Rawls John, Rawls John, Stilgoe Jack, Van den Hoven Jeroen, Van Parijs Philippe, Von Glasenapp Helmuth, Weitz Burkhard   +11 more
core   +1 more source

Delayed and deferred surgery associated with cenobamate use in people with drug‐resistant focal epilepsy

Epilepsia, EarlyView.
Abstract Objective Cenobamate has been shown to be an effective antiseizure medication for some patients with drug‐resistant focal epilepsy being considered for epilepsy surgery. This retrospective single‐center study evaluated whether surgery was obtained within 12 months for patients who received cenobamate as a treatment during the presurgical ...
Jacob Pellinen, Stefan Sillau, Aimee Bui, Alexandra Danciutiu, Lesley Kaye, Ashvin Sood, Louis Ferrari, William E. Rosenfeld, Christopher Elder   +8 more
wiley   +1 more source

Trajectories of quality of life, anxiety and depressive symptomatology, and health‐related work productivity after first seizure events

Epilepsia Open, EarlyView.
Abstract Objective First seizure events are common and may exert an immediate and profound impact on people's lives. Less understood are their long‐term consequences. This prospective, longitudinal study aimed to measure and compare psychosocial and health‐related work productivity trajectories following first seizure events of various etiologies ...
Emma Foster, Zhibin Chen, Alison Conquest, David N. Vaughan, Chris Tailby, Patrick W. Carney, Wendyl D’Souza, Hue Mun Au Yong, John‐Paul Nicolo, Jacob Pellinen, Danny Liew, Terence J. O’Brien, Patrick Kwan, Zanfina Ademi   +13 more
wiley   +1 more source

Demographic composition of National Institutes of Health Clinical and Translational Science Awards (CTSA) Program principal investigators, scholars, and trainees

Journal of Clinical and Translational Science, 2023
Little has been published on the demographic composition of the clinical and translational science research workforce within the Clinical and Translational Science Awards (CTSA) Program despite the well-documented need for greater diversity in the ...
Mercedes Rubio, Heather L. Baker, Jamie Mihoko Doyle   +2 more
doaj   +1 more source

Recent progress on stimuli‐responsive chitosan‐based biomaterials as drug carriers

Interdisciplinary Medicine, EarlyView.
This review discusses the recent progress in chitosan‐based drug delivery systems that respond to pH, redox, enzymes, reactive oxygen species, and combined stimuli. It examines design strategies, key mechanisms, and therapeutic applications, and also addresses current challenges while suggesting future approaches to enhance clinical translation and ...
Changlu Xu, Yi‐Tung Lu, Bin Yang, Zhi Li, Kui Zeng   +4 more
wiley   +1 more source

Ensino da química dos hidrocarbonetos a partir das orientações Ciência, Tecnologia, Sociedade e Ambiente (CTSA)

Revista de Ensino de Ciências e Matemática
É notório a utilização das orientações Ciência, Tecnologia, Sociedade e Ambiente (CTSA) no ensino da Química como possibilidade para a formação de cidadãos críticos e participativos no meio social.
Maria Aparecida da Silva Leite, Severina Coelho da Silva Cantanhede, Leonardo Baltazar Cantanhede   +2 more
doaj   +1 more source

Nurse Engagement and Contributions to the Clinical and Translational Science Awards Initiative [PDF]

, 2013
CTSAs are mandated to follow a multidisciplinary model. Requests for applications direct responsive applications to “integrate clinical and translational science across multiple departments, schools,” listing disciplines in addition to medicine such as ...
Jacob, Jacqueline Dunbar, Knafl, Kathleen A., McCloskey, Donna Jo, Sampselle, Carolyn M.   +3 more
core   +2 more sources

Optimized Detection of Left Ventricular Hyperpolarized [1‐13C]Pyruvate Signal in Human Cardiac Metabolic Imaging

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose This study aimed to improve the analysis of the left ventricular (LV) blood pool hyperpolarized [1‐13C]pyruvate signal for a more reliable quantification of downstream metabolic outcome. Methods Hyperpolarized [1‐13C]pyruvate magnetic resonance spectroscopic images were acquired dynamically at 3 Tesla in 106 participants (NCT03685175).
Fatemeh Khashami, Ivan E. Dimitrov, Maximilian Fuetterer, Stefan Glöggler, Bei Zhang, Egzona Tan, Sebastian Kozerke, Anke Henning, Tarique Hussain, Craig R. Malloy, Nisha Unni, Vlad G. Zaha, CTOX Trial Investigator(s), Sheeba Cantanelli, Isaac Chan, Suzanne Cole, Suzanne Conzen, Glenda Delgado, Deborah Farr, Joshua Gruber, Barbara Haley, Dawn Klemow, Jenny Li, Heather McArthur, Alka Mallik, Poorni Manohar, Ina Patel, Namrata Peswani, Sangeetha Reddy, Navid Sadeghi, Samira Syed   +30 more
wiley   +1 more source