Results 31 to 40 of about 30,262 (239)

Past and future of a century old Citrus tristeza virus collectionA California citrus germplasm tale

Frontiers in Microbiology, 2013
Citrus tristeza virus (CTV) isolates collected from citrus germplasm, dooryard and field trees in California from 1914 have been maintained in planta under quarantine in the Citrus Clonal Protection Program (CCPP), Riverside, California. This collection,
Jinbo eWang, Jinbo eWang, Orhan eBozan, Sun-Jung eKwon, Tyler eDang, Tavia eRucker, Raymond K. Yokomi, Richard F Lee, Svetlana Y Folimonova, Robert R Krueger, John eBash, Greg eGreer, James eDiaz, Ramon eSerna, Georgios eVidalakis   +14 more
doaj   +1 more source

Ionizable Lipid‐Dependent Optimization of Steroid Lipid Nanoparticles With Tunable Immunomodulatory Properties

Advanced Materials, EarlyView.
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte, Benjamin E. Nachod, Julia Baena, Jenna Muscat‐Rivera, Lesley Chaboub, Hannah C. Safford, Hannah C. Geisler, Hannah M. Yamagata, Melgious J. Y. Ang, Michael Kegel, Alexandre Poirier, Elaine R. Tong, Zhe Zhong, Qiangqiang Shi, Jinjin Wang, Elisa Battistini, Ye Zeng, Alex G. Hamilton, Kelsey L. Swingle, Drew Weissman, Jilian R. Melamed, Michael J. Mitchell   +21 more
wiley   +1 more source

Artificial intelligence-generated targets and inter-observer variation in online adaptive radiotherapy of bladder cancer

Physics and Imaging in Radiation Oncology
Background and purpose: Daily target re-delineation in online adaptive radiotherapy (oART) introduces uncertainty. The aim of this study was to evaluate artificial intelligence (AI) generated contours and inter-observer target variation among ...
Lina M. Åström, Patrik Sibolt, Hannah Chamberlin, Eva Serup-Hansen, Claus E. Andersen, Marcel van Herk, Lene S. Mouritsen, Marianne C. Aznar, Claus P. Behrens   +8 more
doaj   +1 more source

Development and Characterization of Monoclonal Antibodies for the Mycotoxin Citreoviridin

Toxins, 2019
Citreoviridin (CTV) in an inhibitor of mitochondrial ATPase that has been isolated from molded yellow rice and linked to the human disease Shoshin-kakke (acute cardiac beriberi).
Chris M. Maragos, Yosuke Uchiyama, Naoki Kobayashi, Fumichika Kominato, Yoshiko Sugita-Konishi   +4 more
doaj   +1 more source

Membrane‐Bound Multimodal Plasmonic Transducers for Noninvasive, In Situ Monitoring and Control of CAR T Cells Against Heterogeneous Solid Tumors

Advanced Materials, EarlyView.
Membrane‐bound multimodal transducers enable longitudinal ultrasound‐guided photoacoustic monitoring and in situ thermal control of CAR T cells in heterogeneous solid tumors. Imaging correlates T cell trafficking with tumor response, distinguishing responders from nonresponders.
Myeongsoo Kim, Ali Zamat, Melissa Cadena, Chloé Thiveaud, Riya Sen, Jeungyoon Lee, Elif Kulaksizoglu, S. Abbey Oliver, Don VanderLaan, Sydney Fábrega, Zizhen Zha, Kelsey P. Kubelick, Jinhwan Kim, Gabriel A. Kwong, Stanislav Y. Emelianov   +14 more
wiley   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Summary of sedimentation coefficients (s) for EF hand mutants of CTV-TnC: D104A CTV, D140A CTV, D104-140A CTV.

, 2016
Summary of sedimentation coefficients (s) for EF hand mutants of CTV-TnC: D104A CTV, D140A CTV, D104-140A CTV.
Myriam A. Badr (3219207), Jose R. Pinto (3219204), P. Bryant Chase (156969), Michael W. Davidson (112687)   +3 more
core   +1 more source

SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer

Advanced Science, EarlyView.
Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian, Teizo Yoshimura, Kun Zhao, Chunning Li, Tong Gao, Ziyi Wang, Masayoshi Fujisawa, Toshiaki Ohara, Akihiro Matsukawa   +8 more
wiley   +1 more source

Transcriptional analysis of sweet orange trees co-infected with ‘Candidatus Liberibacter asiaticus’ and mild or severe strains of Citrus tristeza virus

BMC Genomics, 2017
Background Citrus worldwide is threatened by huanglongbing (HLB) and tristeza diseases caused by ‘Candidatus Liberibacter asiaticus’ (CaLas) and Citrus tristeza virus (CTV).
Shimin Fu, Jonathan Shao, Cristina Paul, Changyong Zhou, John S. Hartung   +4 more
doaj   +1 more source

Question period : round table on the G20; 18 Nov. 2001

, 2001
Transcription of CTV news program in HTML formatSupplied titleIDRC president Maureen O'Neil takes part in a round table on the G20, along with Canadian journalist Ed Greenspon and hosts Rodger Smith and Craig ...
O'Neil, M., CTV Television Network, Greenspon, E., Craig, O., Smith, R.   +4 more
core   +1 more source