Results 1 to 10 of about 333,136 (300)

Transcranial Magnetic Stimulation as a Translational Biomarker in Early-Phase Anti-Seizure Medication Development: A Randomized, Double-Blind, Placebo-Controlled Study in Generalized Epilepsy. [PDF]

Clin Pharmacol Ther
One‐third of epilepsy patients remain treatment‐resistant, underscoring the need for novel anti‐seizure medications (ASMs) and reliable biomarkers of central target engagement. Cortical hyperexcitability is a hallmark of epilepsy, making excitability a valuable pharmacodynamic biomarker for early‐phase drug development supporting go/no‐go decision ...
de Cuba CME, Ruijs TQ, de Goede AA, Doll RJ, Juachon M, van Putten MJAM, Groeneveld GJ, Heuberger JAAC.   +7 more
europepmc   +2 more sources

Reconstructing IDF curves from daily rainfall records in data-scarce regions: A statistical method based on temporal disaggregation and gumbel modeling. [PDF]

PLoS One
Molino J, Martí-Fis H, Rodriguez-López Y.   +2 more
europepmc   +1 more source

The SALV-Dataset Registry: An Expertly Curated Digital Clinicopathological Dataset for Salivary Gland Tumor Research and AI-Assisted Diagnostic Tools. [PDF]

Head Neck Pathol
Burghout KST, Weijer JAJ, Evers AC, Breimer GE, van Rossem JN, Peferoen LAN, Bloemena E, Koppes SA, van Dis V, Verdijk RM, van Engen-van Grunsven I, Doeleman T, van den Hout MFCM, van der Vegt B, Doff JJ, Hazelbag HM, Smit LA, de Cuba EMV, Ooft ML, Rupp NJ, Steeghs EMP, de Ridder M, de Bree R, Slingerland M, Smit VTHBM, van Egmond SL, Cohen D.   +26 more
europepmc   +1 more source

Enhancing Healthcare Services for Vulnerable Aging Populations: A Comparative Analysis of Puerto Rico and International Case Studies. [PDF]

Healthcare (Basel)
Nannuri V, Belligoni S, Sulkouskaya D, Shah R, Pathak O, Rivera FI.   +5 more
europepmc   +1 more source

The implementation gap: how Cuba's tuberculosis setback exposes a universal challenge for low-burden countries. [PDF]

Lancet Reg Health Am
Martínez-Rodríguez A, González-Díaz A, de Los Angeles León Venero M, García CP, Toledo Romaní ME.   +4 more
europepmc   +1 more source

Viruses Infecting Cuban Honey Bees and Evolution of Deformed-Wing-Virus Variants. [PDF]

Viruses
Hesketh-Best PJ, Luis AR, Schroeder DC, Martin SJ.   +3 more
europepmc   +1 more source

Improving the Identification of the Preclinical Stages of Spinocerebellar Ataxia Type 2. [PDF]

Tomography
Mora-Batista C, Vargas-De-León C, Reyes-Carreto R, Carrillo-Rodes FJ, Álvarez-Cuesta JA.   +4 more
europepmc   +1 more source

Role of family medicine on health systems in the Americas: scoping review. [PDF]

Fam Med Community Health
Hernandez Rincon EH, Hernandez Rincon JA, Saza Salas LD, Ulloa Roddriguez MF, Jaimes Peñuela CL, Diaz Quijano DM.   +5 more
europepmc   +1 more source

An Information-Geometric Justification for Composite Coherence in Event-Based Narrative Extraction. [PDF]

Entropy (Basel)
Keith-Norambuena B.
europepmc   +1 more source

Efficacy of Manuka honey eye drops in managing dry eye disease after cataract surgery: a prospective controlled study. [PDF]

Front Ophthalmol (Lausanne)
García-Bardera J, García-Bella J, Cuba-Sulluchuco FK, Burgos-Blasco B, Arriola-Villalobos P, Benítez-Del-Castillo JM.   +5 more
europepmc   +1 more source