A Human‐Based Skin‐Lymphoreticular Model‐on‐Chip to Emulate Inflammatory Skin Conditions
Advanced Healthcare Materials, EarlyView.A human‐based lymphoreticular (LR) model was developed through guided self‐assembly and integrated in a skin‐lymphoreticular co‐culture in a microfluidic organ‐on‐chip to mimic interactions between skin and its draining lymph nodes. The human‐based skin‐lymphoreticular model resembles a minimally functional unit that allows to study interactions ...
Zheng Tan +3 more
wiley +1 more source
Integration of affective cues in context-rich and dynamic scenes varies across individuals. [PDF]
Nat CommunOrtega J, Murai Y, Whitney D.
europepmc +1 more source
Microphysiological Systems of Lymphatics and Immune Organs
Advanced Healthcare Materials, EarlyView.This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain +2 more
wiley +1 more source
Taste of Things to Come: Craving Responses to Ingestion of and Mouth Rinse with a Sugary Drink in Connection with Food Cues and Associations with Continuous Interstitial Glucose Measurement in a Healthy Population. [PDF]
NutrientsAl Gamode A +3 more
europepmc +1 more source
Development of a Synthetic 3D Platform for Compartmentalized Kidney In Vitro Disease Modeling
Advanced Healthcare Materials, EarlyView.A fully synthetic, compartmentalized 3D kidney disease model is introduced. The kidney model combines a PEG‐based hydrogel matrix with anisotropic, enzymatically degradable rod‐shaped microgels to spatially arrange a triple co‐culture of key renal epithelial, endothelial, and fibroblast cells.
Ninon Möhl +8 more
wiley +1 more source
The anticipation of imminent events is time-scale invariant. [PDF]
Proc Natl Acad Sci U S AGrabenhorst M, Poeppel D, Michalareas G.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Commercial vascular grafts are made from ePTFE, a highly hydrophobic, foreign material that fails at a high rate in small‐diameter applications. Plasma polymer nanoparticles (PPN) are a versatile material functionalisation tool, used here to present fibrillin‐1 fragment PF8 on the graft surface.
Bob S. L. Lee +9 more
wiley +1 more source
Linear and nonlinear effects of Spatial and Temporal attention: human data and drift diffusion model. [PDF]
Sci RepChristian IR +4 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues +6 more
wiley +1 more source
Pre-Decisional Information Search in 2- to 4-Year-Olds: Young Children Select the Relevant Cues When Looking for a Hidden Reward. [PDF]
Dev SciSerko D, Li YL, Swaboda N, Ruggeri A.
europepmc +1 more source